TNIK-MTHFD1L Fusion FISH Probe
The TNIK-MTHFD1L Fusion FISH Probe is used to confirm a fusion of the TNIK and MTHFD1L genes. The fusion of the TNIK and MTHFD1L genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TNIK-MTHFD1L-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TNIK-MTHFD1L-20-RERE | 20 (40 μL) | 200 μL |
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| TNIK-MTHFD1L-20-REOR | 20 (40 μL) | 200 μL |
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| TNIK-MTHFD1L-20-REGO | 20 (40 μL) | 200 μL |
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| TNIK-MTHFD1L-20-REGR | 20 (40 μL) | 200 μL |
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| TNIK-MTHFD1L-20-REAQ | 20 (40 μL) | 200 μL |
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| TNIK-MTHFD1L-20-ORRE | 20 (40 μL) | 200 μL |
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| TNIK-MTHFD1L-20-OROR | 20 (40 μL) | 200 μL |
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| TNIK-MTHFD1L-20-ORGO | 20 (40 μL) | 200 μL |
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| TNIK-MTHFD1L-20-ORAQ | 20 (40 μL) | 200 μL |
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| TNIK-MTHFD1L-20-GORE | 20 (40 μL) | 200 μL |
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| TNIK-MTHFD1L-20-GOOR | 20 (40 μL) | 200 μL |
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| TNIK-MTHFD1L-20-GOGO | 20 (40 μL) | 200 μL |
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| TNIK-MTHFD1L-20-GOGR | 20 (40 μL) | 200 μL |
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| TNIK-MTHFD1L-20-GOAQ | 20 (40 μL) | 200 μL |
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| TNIK-MTHFD1L-20-GRRE | 20 (40 μL) | 200 μL |
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| TNIK-MTHFD1L-20-GROR | 20 (40 μL) | 200 μL |
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| TNIK-MTHFD1L-20-GRGO | 20 (40 μL) | 200 μL |
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| TNIK-MTHFD1L-20-GRGR | 20 (40 μL) | 200 μL |
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| TNIK-MTHFD1L-20-GRAQ | 20 (40 μL) | 200 μL |
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| TNIK-MTHFD1L-20-AQRE | 20 (40 μL) | 200 μL |
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| TNIK-MTHFD1L-20-AQOR | 20 (40 μL) | 200 μL |
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| TNIK-MTHFD1L-20-AQGO | 20 (40 μL) | 200 μL |
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| TNIK-MTHFD1L-20-AQGR | 20 (40 μL) | 200 μL |
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| TNIK-MTHFD1L-20-AQAQ | 20 (40 μL) | 200 μL |
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TNIK Gene Summary
Wnt signaling plays important roles in carcinogenesis and embryonic development. The protein encoded by this gene is a serine/threonine kinase that functions as an activator of the Wnt signaling pathway. Mutations in this gene are associated with an autosomal recessive form of cognitive disability. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2017]
Gene Name: TRAF2 And NCK Interacting Kinase
Chromosome: CHR3: 170780291 -171178197
Locus: 3q26.2-q26.31
MTHFD1L Gene Summary
The protein encoded by this gene is involved in the synthesis of tetrahydrofolate (THF) in the mitochondrion. THF is important in the de novo synthesis of purines and thymidylate and in the regeneration of methionine from homocysteine. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2011]
Gene Name: Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1 Like
Chromosome: CHR6: 151186814 -151423023
Locus: 6q25.1
Gene Diseases
The TNIK MTHFD1L Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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