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TNFSF14-GRAMD1A Fusion FISH Probe

The TNFSF14-GRAMD1A Fusion FISH Probe is used to confirm a fusion of the TNFSF14 and GRAMD1A genes. The fusion of the TNFSF14 and GRAMD1A genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
TNFSF14-GRAMD1A-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
TNFSF14-GRAMD1A-20-RERE 20 (40 μL) 200 μL
TNFSF14-GRAMD1A-20-REOR 20 (40 μL) 200 μL
TNFSF14-GRAMD1A-20-REGO 20 (40 μL) 200 μL
TNFSF14-GRAMD1A-20-REGR 20 (40 μL) 200 μL
TNFSF14-GRAMD1A-20-REAQ 20 (40 μL) 200 μL
TNFSF14-GRAMD1A-20-ORRE 20 (40 μL) 200 μL
TNFSF14-GRAMD1A-20-OROR 20 (40 μL) 200 μL
TNFSF14-GRAMD1A-20-ORGO 20 (40 μL) 200 μL
TNFSF14-GRAMD1A-20-ORAQ 20 (40 μL) 200 μL
TNFSF14-GRAMD1A-20-GORE 20 (40 μL) 200 μL
TNFSF14-GRAMD1A-20-GOOR 20 (40 μL) 200 μL
TNFSF14-GRAMD1A-20-GOGO 20 (40 μL) 200 μL
TNFSF14-GRAMD1A-20-GOGR 20 (40 μL) 200 μL
TNFSF14-GRAMD1A-20-GOAQ 20 (40 μL) 200 μL
TNFSF14-GRAMD1A-20-GRRE 20 (40 μL) 200 μL
TNFSF14-GRAMD1A-20-GROR 20 (40 μL) 200 μL
TNFSF14-GRAMD1A-20-GRGO 20 (40 μL) 200 μL
TNFSF14-GRAMD1A-20-GRGR 20 (40 μL) 200 μL
TNFSF14-GRAMD1A-20-GRAQ 20 (40 μL) 200 μL
TNFSF14-GRAMD1A-20-AQRE 20 (40 μL) 200 μL
TNFSF14-GRAMD1A-20-AQOR 20 (40 μL) 200 μL
TNFSF14-GRAMD1A-20-AQGO 20 (40 μL) 200 μL
TNFSF14-GRAMD1A-20-AQGR 20 (40 μL) 200 μL
TNFSF14-GRAMD1A-20-AQAQ 20 (40 μL) 200 μL

TNFSF14 Gene Summary

The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry mediator (HVEM). This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Gene Name: TNF Superfamily Member 14

Chromosome: CHR19: 6663147 -6670599

Locus: 19p13.3

GRAMD1A Gene Summary

The GRAM Domain Containing 1A (GRAMD1A) gene is located on chr19 :35491245-35517373 at 19q13.11.

Gene Name: GRAM Domain Containing 1A

Chromosome: CHR19: 35491245 -35517373

Locus: 19q13.11

Gene Diseases

The TNFSF14 GRAMD1A Fusion has been associated with the following diseases:

Disease Name
Head And Neck Squamous Cell Carcinoma 

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.