TNFAIP8-DMXL1 Fusion FISH Probe
The TNFAIP8-DMXL1 Fusion FISH Probe is used to confirm a fusion of the TNFAIP8 and DMXL1 genes. The fusion of the TNFAIP8 and DMXL1 genes has been associated with Pheochromocytoma And Paraganglioma, and Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TNFAIP8-DMXL1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TNFAIP8-DMXL1-20-RERE | 20 (40 μL) | 200 μL |
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| TNFAIP8-DMXL1-20-REOR | 20 (40 μL) | 200 μL |
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| TNFAIP8-DMXL1-20-REGO | 20 (40 μL) | 200 μL |
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| TNFAIP8-DMXL1-20-REGR | 20 (40 μL) | 200 μL |
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| TNFAIP8-DMXL1-20-REAQ | 20 (40 μL) | 200 μL |
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| TNFAIP8-DMXL1-20-ORRE | 20 (40 μL) | 200 μL |
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| TNFAIP8-DMXL1-20-OROR | 20 (40 μL) | 200 μL |
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| TNFAIP8-DMXL1-20-ORGO | 20 (40 μL) | 200 μL |
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| TNFAIP8-DMXL1-20-ORAQ | 20 (40 μL) | 200 μL |
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| TNFAIP8-DMXL1-20-GORE | 20 (40 μL) | 200 μL |
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| TNFAIP8-DMXL1-20-GOOR | 20 (40 μL) | 200 μL |
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| TNFAIP8-DMXL1-20-GOGO | 20 (40 μL) | 200 μL |
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| TNFAIP8-DMXL1-20-GOGR | 20 (40 μL) | 200 μL |
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| TNFAIP8-DMXL1-20-GOAQ | 20 (40 μL) | 200 μL |
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| TNFAIP8-DMXL1-20-GRRE | 20 (40 μL) | 200 μL |
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| TNFAIP8-DMXL1-20-GROR | 20 (40 μL) | 200 μL |
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| TNFAIP8-DMXL1-20-GRGO | 20 (40 μL) | 200 μL |
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| TNFAIP8-DMXL1-20-GRGR | 20 (40 μL) | 200 μL |
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| TNFAIP8-DMXL1-20-GRAQ | 20 (40 μL) | 200 μL |
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| TNFAIP8-DMXL1-20-AQRE | 20 (40 μL) | 200 μL |
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| TNFAIP8-DMXL1-20-AQOR | 20 (40 μL) | 200 μL |
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| TNFAIP8-DMXL1-20-AQGO | 20 (40 μL) | 200 μL |
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| TNFAIP8-DMXL1-20-AQGR | 20 (40 μL) | 200 μL |
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| TNFAIP8-DMXL1-20-AQAQ | 20 (40 μL) | 200 μL |
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DMXL1 Gene Summary
The protein encoded by this gene is a member of the WD repeat superfamily of proteins, which have regulatory functions. This gene is expressed in many tissue types including several types of eye tissue, and it has been associated with ocular phenotypes. In addition, it is upregulated in cultured cells that overexpress growth factor independence 1B, a transcription factor that is essential for hematopoietic cell development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
Gene Name: Dmx Like 1
Chromosome: CHR5: 118407083 -118584822
Locus: 5q23.1
TNFAIP8 Gene Summary
The TNF Alpha Induced Protein 8 (TNFAIP8) gene is located on chr5 :118604417-118730294 at 5q23.1.
Gene Name: TNF Alpha Induced Protein 8
Chromosome: CHR5: 118604417 -118730294
Locus: 5q23.1
Gene Diseases
The TNFAIP8 DMXL1 Fusion has been associated with the following diseases:
| Disease Name |
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| Pheochromocytoma And Paraganglioma |
| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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