TMX1-TRIM9 Fusion FISH Probe
The TMX1-TRIM9 Fusion FISH Probe is used to confirm a fusion of the TMX1 and TRIM9 genes. The fusion of the TMX1 and TRIM9 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TMX1-TRIM9-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TMX1-TRIM9-20-RERE | 20 (40 μL) | 200 μL |
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| TMX1-TRIM9-20-REOR | 20 (40 μL) | 200 μL |
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| TMX1-TRIM9-20-REGO | 20 (40 μL) | 200 μL |
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| TMX1-TRIM9-20-REGR | 20 (40 μL) | 200 μL |
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| TMX1-TRIM9-20-REAQ | 20 (40 μL) | 200 μL |
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| TMX1-TRIM9-20-ORRE | 20 (40 μL) | 200 μL |
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| TMX1-TRIM9-20-OROR | 20 (40 μL) | 200 μL |
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| TMX1-TRIM9-20-ORGO | 20 (40 μL) | 200 μL |
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| TMX1-TRIM9-20-ORAQ | 20 (40 μL) | 200 μL |
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| TMX1-TRIM9-20-GORE | 20 (40 μL) | 200 μL |
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| TMX1-TRIM9-20-GOOR | 20 (40 μL) | 200 μL |
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| TMX1-TRIM9-20-GOGO | 20 (40 μL) | 200 μL |
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| TMX1-TRIM9-20-GOGR | 20 (40 μL) | 200 μL |
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| TMX1-TRIM9-20-GOAQ | 20 (40 μL) | 200 μL |
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| TMX1-TRIM9-20-GRRE | 20 (40 μL) | 200 μL |
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| TMX1-TRIM9-20-GROR | 20 (40 μL) | 200 μL |
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| TMX1-TRIM9-20-GRGO | 20 (40 μL) | 200 μL |
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| TMX1-TRIM9-20-GRGR | 20 (40 μL) | 200 μL |
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| TMX1-TRIM9-20-GRAQ | 20 (40 μL) | 200 μL |
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| TMX1-TRIM9-20-AQRE | 20 (40 μL) | 200 μL |
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| TMX1-TRIM9-20-AQOR | 20 (40 μL) | 200 μL |
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| TMX1-TRIM9-20-AQGO | 20 (40 μL) | 200 μL |
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| TMX1-TRIM9-20-AQGR | 20 (40 μL) | 200 μL |
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| TMX1-TRIM9-20-AQAQ | 20 (40 μL) | 200 μL |
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TMX1 Gene Summary
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and one transmembrane domain. Unlike most members of this gene family, it lacks a C-terminal ER-retention sequence. The mature membrane-bound protein can both oxidize and reduce disulfide bonds and acts selectively on membrane-associated polypeptides. [provided by RefSeq, Jan 2017]
Gene Name: Thioredoxin Related Transmembrane Protein 1
Chromosome: CHR14: 51706885 -51724372
Locus: 14q22.1
TRIM9 Gene Summary
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Its function has not been identified. Alternate splicing of this gene generates two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Name: Tripartite Motif Containing 9
Chromosome: CHR14: 51441980 -51562422
Locus: 14q22.1
Gene Diseases
The TMX1 TRIM9 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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