TMTC4-FGF14 Fusion FISH Probe
The TMTC4-FGF14 Fusion FISH Probe is used to confirm a fusion of the TMTC4 and FGF14 genes. The fusion of the TMTC4 and FGF14 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TMTC4-FGF14-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TMTC4-FGF14-20-RERE | 20 (40 μL) | 200 μL |
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| TMTC4-FGF14-20-REOR | 20 (40 μL) | 200 μL |
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| TMTC4-FGF14-20-REGO | 20 (40 μL) | 200 μL |
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| TMTC4-FGF14-20-REGR | 20 (40 μL) | 200 μL |
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| TMTC4-FGF14-20-REAQ | 20 (40 μL) | 200 μL |
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| TMTC4-FGF14-20-ORRE | 20 (40 μL) | 200 μL |
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| TMTC4-FGF14-20-OROR | 20 (40 μL) | 200 μL |
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| TMTC4-FGF14-20-ORGO | 20 (40 μL) | 200 μL |
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| TMTC4-FGF14-20-ORAQ | 20 (40 μL) | 200 μL |
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| TMTC4-FGF14-20-GORE | 20 (40 μL) | 200 μL |
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| TMTC4-FGF14-20-GOOR | 20 (40 μL) | 200 μL |
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| TMTC4-FGF14-20-GOGO | 20 (40 μL) | 200 μL |
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| TMTC4-FGF14-20-GOGR | 20 (40 μL) | 200 μL |
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| TMTC4-FGF14-20-GOAQ | 20 (40 μL) | 200 μL |
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| TMTC4-FGF14-20-GRRE | 20 (40 μL) | 200 μL |
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| TMTC4-FGF14-20-GROR | 20 (40 μL) | 200 μL |
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| TMTC4-FGF14-20-GRGO | 20 (40 μL) | 200 μL |
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| TMTC4-FGF14-20-GRGR | 20 (40 μL) | 200 μL |
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| TMTC4-FGF14-20-GRAQ | 20 (40 μL) | 200 μL |
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| TMTC4-FGF14-20-AQRE | 20 (40 μL) | 200 μL |
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| TMTC4-FGF14-20-AQOR | 20 (40 μL) | 200 μL |
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| TMTC4-FGF14-20-AQGO | 20 (40 μL) | 200 μL |
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| TMTC4-FGF14-20-AQGR | 20 (40 μL) | 200 μL |
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| TMTC4-FGF14-20-AQAQ | 20 (40 μL) | 200 μL |
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FGF14 Gene Summary
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. A mutation in this gene is associated with autosomal dominant cerebral ataxia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Fibroblast Growth Factor 14
Chromosome: CHR13: 102373204 -103054124
Locus: 13q33.1
TMTC4 Gene Summary
This gene encodes a transmembrane protein that belongs to family of proteins containing an N-terminal transmembrane domain and a C-terminal tetratricopeptide repeat (TPR) domain. TPR domains mediate protein-protein interactions in various cellular processes, such as synaptic vesicle fusion, protein folding, and protein translocation. A pseudogene of this gene has been defined on chromosome 5. [provided by RefSeq, Apr 2017]
Gene Name: Transmembrane And Tetratricopeptide Repeat Containing 4
Chromosome: CHR13: 101256089 -101327103
Locus: 13q32.3
Gene Diseases
The TMTC4 FGF14 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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