TMTC2-HERC1 Fusion FISH Probe
The TMTC2-HERC1 Fusion FISH Probe is used to confirm a fusion of the TMTC2 and HERC1 genes. The fusion of the TMTC2 and HERC1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TMTC2-HERC1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TMTC2-HERC1-20-RERE | 20 (40 μL) | 200 μL |
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| TMTC2-HERC1-20-REOR | 20 (40 μL) | 200 μL |
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| TMTC2-HERC1-20-REGO | 20 (40 μL) | 200 μL |
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| TMTC2-HERC1-20-REGR | 20 (40 μL) | 200 μL |
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| TMTC2-HERC1-20-REAQ | 20 (40 μL) | 200 μL |
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| TMTC2-HERC1-20-ORRE | 20 (40 μL) | 200 μL |
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| TMTC2-HERC1-20-OROR | 20 (40 μL) | 200 μL |
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| TMTC2-HERC1-20-ORGO | 20 (40 μL) | 200 μL |
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| TMTC2-HERC1-20-ORAQ | 20 (40 μL) | 200 μL |
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| TMTC2-HERC1-20-GORE | 20 (40 μL) | 200 μL |
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| TMTC2-HERC1-20-GOOR | 20 (40 μL) | 200 μL |
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| TMTC2-HERC1-20-GOGO | 20 (40 μL) | 200 μL |
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| TMTC2-HERC1-20-GOGR | 20 (40 μL) | 200 μL |
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| TMTC2-HERC1-20-GOAQ | 20 (40 μL) | 200 μL |
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| TMTC2-HERC1-20-GRRE | 20 (40 μL) | 200 μL |
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| TMTC2-HERC1-20-GROR | 20 (40 μL) | 200 μL |
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| TMTC2-HERC1-20-GRGO | 20 (40 μL) | 200 μL |
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| TMTC2-HERC1-20-GRGR | 20 (40 μL) | 200 μL |
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| TMTC2-HERC1-20-GRAQ | 20 (40 μL) | 200 μL |
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| TMTC2-HERC1-20-AQRE | 20 (40 μL) | 200 μL |
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| TMTC2-HERC1-20-AQOR | 20 (40 μL) | 200 μL |
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| TMTC2-HERC1-20-AQGO | 20 (40 μL) | 200 μL |
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| TMTC2-HERC1-20-AQGR | 20 (40 μL) | 200 μL |
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| TMTC2-HERC1-20-AQAQ | 20 (40 μL) | 200 μL |
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HERC1 Gene Summary
This gen encodes a member of the HERC protein family. This protein stimulates guanine nucleotide exchange on ARF1 and Rab proteins. This protein may be involved in membrane transport processes. [provided by RefSeq, Mar 2012]
Gene Name: HECT And RLD Domain Containing E3 Ubiquitin Protein Ligase Family Member 1
Chromosome: CHR15: 63900816 -64126147
Locus: 15q22.31
TMTC2 Gene Summary
The protein encoded by this gene is an integral membrane protein localized to the endoplasmic reticulum (ER). The encoded protein contains many tetratricopeptide repeats, sequences known for being involved in protein-protein interactions. This protein binds both the calcium uptake pump SERCA2B and the carbohydrate-binding chaperone calnexin, and it appears to play a role in calcium homeostasis in the ER. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]
Gene Name: Transmembrane And Tetratricopeptide Repeat Containing 2
Chromosome: CHR12: 83080933 -83528067
Locus: 12q21.31
Gene Diseases
The TMTC2 HERC1 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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