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TMEM63B-POLR1C Fusion FISH Probe

The TMEM63B-POLR1C Fusion FISH Probe is used to confirm a fusion of the TMEM63B and POLR1C genes. The fusion of the TMEM63B and POLR1C genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
TMEM63B-POLR1C-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
TMEM63B-POLR1C-20-RERE 20 (40 μL) 200 μL
TMEM63B-POLR1C-20-REOR 20 (40 μL) 200 μL
TMEM63B-POLR1C-20-REGO 20 (40 μL) 200 μL
TMEM63B-POLR1C-20-REGR 20 (40 μL) 200 μL
TMEM63B-POLR1C-20-REAQ 20 (40 μL) 200 μL
TMEM63B-POLR1C-20-ORRE 20 (40 μL) 200 μL
TMEM63B-POLR1C-20-OROR 20 (40 μL) 200 μL
TMEM63B-POLR1C-20-ORGO 20 (40 μL) 200 μL
TMEM63B-POLR1C-20-ORAQ 20 (40 μL) 200 μL
TMEM63B-POLR1C-20-GORE 20 (40 μL) 200 μL
TMEM63B-POLR1C-20-GOOR 20 (40 μL) 200 μL
TMEM63B-POLR1C-20-GOGO 20 (40 μL) 200 μL
TMEM63B-POLR1C-20-GOGR 20 (40 μL) 200 μL
TMEM63B-POLR1C-20-GOAQ 20 (40 μL) 200 μL
TMEM63B-POLR1C-20-GRRE 20 (40 μL) 200 μL
TMEM63B-POLR1C-20-GROR 20 (40 μL) 200 μL
TMEM63B-POLR1C-20-GRGO 20 (40 μL) 200 μL
TMEM63B-POLR1C-20-GRGR 20 (40 μL) 200 μL
TMEM63B-POLR1C-20-GRAQ 20 (40 μL) 200 μL
TMEM63B-POLR1C-20-AQRE 20 (40 μL) 200 μL
TMEM63B-POLR1C-20-AQOR 20 (40 μL) 200 μL
TMEM63B-POLR1C-20-AQGO 20 (40 μL) 200 μL
TMEM63B-POLR1C-20-AQGR 20 (40 μL) 200 μL
TMEM63B-POLR1C-20-AQAQ 20 (40 μL) 200 μL

POLR1C Gene Summary

The protein encoded by this gene is a subunit of both RNA polymerase I and RNA polymerase III complexes. The encoded protein is part of the Pol core element. Mutations in this gene have been associated with Treacher Collins syndrome (TCS) and hypomyelinating leukodystrophy 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

Gene Name: RNA Polymerase I Subunit C

Chromosome: CHR6: 43484776 -43489246

Locus: 6p21.1

TMEM63B Gene Summary

The Transmembrane Protein 63B (TMEM63B) gene is located on chr6 :44095375-44123256 at 6p21.1.

Gene Name: Transmembrane Protein 63B

Chromosome: CHR6: 44095375 -44123256

Locus: 6p21.1

Gene Diseases

The TMEM63B POLR1C Fusion has been associated with the following diseases:

Disease Name
Liver Hepatocellular Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.