TMEM59-MYBPC1 Fusion FISH Probe
The TMEM59-MYBPC1 Fusion FISH Probe is used to confirm a fusion of the TMEM59 and MYBPC1 genes. The fusion of the TMEM59 and MYBPC1 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TMEM59-MYBPC1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TMEM59-MYBPC1-20-RERE | 20 (40 μL) | 200 μL |
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| TMEM59-MYBPC1-20-REOR | 20 (40 μL) | 200 μL |
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| TMEM59-MYBPC1-20-REGO | 20 (40 μL) | 200 μL |
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| TMEM59-MYBPC1-20-REGR | 20 (40 μL) | 200 μL |
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| TMEM59-MYBPC1-20-REAQ | 20 (40 μL) | 200 μL |
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| TMEM59-MYBPC1-20-ORRE | 20 (40 μL) | 200 μL |
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| TMEM59-MYBPC1-20-OROR | 20 (40 μL) | 200 μL |
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| TMEM59-MYBPC1-20-ORGO | 20 (40 μL) | 200 μL |
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| TMEM59-MYBPC1-20-ORAQ | 20 (40 μL) | 200 μL |
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| TMEM59-MYBPC1-20-GORE | 20 (40 μL) | 200 μL |
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| TMEM59-MYBPC1-20-GOOR | 20 (40 μL) | 200 μL |
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| TMEM59-MYBPC1-20-GOGO | 20 (40 μL) | 200 μL |
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| TMEM59-MYBPC1-20-GOGR | 20 (40 μL) | 200 μL |
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| TMEM59-MYBPC1-20-GOAQ | 20 (40 μL) | 200 μL |
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| TMEM59-MYBPC1-20-GRRE | 20 (40 μL) | 200 μL |
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| TMEM59-MYBPC1-20-GROR | 20 (40 μL) | 200 μL |
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| TMEM59-MYBPC1-20-GRGO | 20 (40 μL) | 200 μL |
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| TMEM59-MYBPC1-20-GRGR | 20 (40 μL) | 200 μL |
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| TMEM59-MYBPC1-20-GRAQ | 20 (40 μL) | 200 μL |
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| TMEM59-MYBPC1-20-AQRE | 20 (40 μL) | 200 μL |
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| TMEM59-MYBPC1-20-AQOR | 20 (40 μL) | 200 μL |
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| TMEM59-MYBPC1-20-AQGO | 20 (40 μL) | 200 μL |
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| TMEM59-MYBPC1-20-AQGR | 20 (40 μL) | 200 μL |
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| TMEM59-MYBPC1-20-AQAQ | 20 (40 μL) | 200 μL |
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MYBPC1 Gene Summary
This gene encodes a member of the myosin-binding protein C family. Myosin-binding protein C family members are myosin-associated proteins found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. The encoded protein is the slow skeletal muscle isoform of myosin-binding protein C and plays an important role in muscle contraction by recruiting muscle-type creatine kinase to myosin filaments. Mutations in this gene are associated with distal arthrogryposis type I. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Gene Name: Myosin Binding Protein C, Slow Type
Chromosome: CHR12: 101988746 -102079658
Locus: 12q23.2
TMEM59 Gene Summary
This gene encodes a protein shown to regulate autophagy in response to bacterial infection. This protein may also regulate the retention of amyloid precursor protein (APP) in the Golgi apparatus through its control of APP glycosylation. Overexpression of this protein has been found to promote apoptosis in a glioma cell line. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]
Gene Name: Transmembrane Protein 59
Chromosome: CHR1: 54497348 -54519111
Locus: 1p32.3
Gene Diseases
The TMEM59 MYBPC1 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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