TMEM182-IL18R1 Fusion FISH Probe
The TMEM182-IL18R1 Fusion FISH Probe is used to confirm a fusion of the TMEM182 and IL18R1 genes. The fusion of the TMEM182 and IL18R1 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TMEM182-IL18R1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TMEM182-IL18R1-20-RERE | 20 (40 μL) | 200 μL |
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| TMEM182-IL18R1-20-REOR | 20 (40 μL) | 200 μL |
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| TMEM182-IL18R1-20-REGO | 20 (40 μL) | 200 μL |
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| TMEM182-IL18R1-20-REGR | 20 (40 μL) | 200 μL |
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| TMEM182-IL18R1-20-REAQ | 20 (40 μL) | 200 μL |
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| TMEM182-IL18R1-20-ORRE | 20 (40 μL) | 200 μL |
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| TMEM182-IL18R1-20-OROR | 20 (40 μL) | 200 μL |
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| TMEM182-IL18R1-20-ORGO | 20 (40 μL) | 200 μL |
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| TMEM182-IL18R1-20-ORAQ | 20 (40 μL) | 200 μL |
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| TMEM182-IL18R1-20-GORE | 20 (40 μL) | 200 μL |
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| TMEM182-IL18R1-20-GOOR | 20 (40 μL) | 200 μL |
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| TMEM182-IL18R1-20-GOGO | 20 (40 μL) | 200 μL |
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| TMEM182-IL18R1-20-GOGR | 20 (40 μL) | 200 μL |
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| TMEM182-IL18R1-20-GOAQ | 20 (40 μL) | 200 μL |
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| TMEM182-IL18R1-20-GRRE | 20 (40 μL) | 200 μL |
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| TMEM182-IL18R1-20-GROR | 20 (40 μL) | 200 μL |
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| TMEM182-IL18R1-20-GRGO | 20 (40 μL) | 200 μL |
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| TMEM182-IL18R1-20-GRGR | 20 (40 μL) | 200 μL |
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| TMEM182-IL18R1-20-GRAQ | 20 (40 μL) | 200 μL |
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| TMEM182-IL18R1-20-AQRE | 20 (40 μL) | 200 μL |
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| TMEM182-IL18R1-20-AQOR | 20 (40 μL) | 200 μL |
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| TMEM182-IL18R1-20-AQGO | 20 (40 μL) | 200 μL |
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| TMEM182-IL18R1-20-AQGR | 20 (40 μL) | 200 μL |
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| TMEM182-IL18R1-20-AQAQ | 20 (40 μL) | 200 μL |
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IL18R1 Gene Summary
The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]
Gene Name: Interleukin 18 Receptor 1
Chromosome: CHR2: 102979096 -103015217
Locus: 2q12.1
TMEM182 Gene Summary
The Transmembrane Protein 182 (TMEM182) gene is located on chr2 :103378489-103434138 at 2q12.1.
Gene Name: Transmembrane Protein 182
Chromosome: CHR2: 103378489 -103434138
Locus: 2q12.1
Gene Diseases
The TMEM182 IL18R1 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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