TMEM117-ZCRB1 Fusion FISH Probe
The TMEM117-ZCRB1 Fusion FISH Probe is used to confirm a fusion of the TMEM117 and ZCRB1 genes. The fusion of the TMEM117 and ZCRB1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TMEM117-ZCRB1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TMEM117-ZCRB1-20-RERE | 20 (40 μL) | 200 μL |
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| TMEM117-ZCRB1-20-REOR | 20 (40 μL) | 200 μL |
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| TMEM117-ZCRB1-20-REGO | 20 (40 μL) | 200 μL |
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| TMEM117-ZCRB1-20-REGR | 20 (40 μL) | 200 μL |
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| TMEM117-ZCRB1-20-REAQ | 20 (40 μL) | 200 μL |
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| TMEM117-ZCRB1-20-ORRE | 20 (40 μL) | 200 μL |
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| TMEM117-ZCRB1-20-OROR | 20 (40 μL) | 200 μL |
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| TMEM117-ZCRB1-20-ORGO | 20 (40 μL) | 200 μL |
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| TMEM117-ZCRB1-20-ORAQ | 20 (40 μL) | 200 μL |
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| TMEM117-ZCRB1-20-GORE | 20 (40 μL) | 200 μL |
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| TMEM117-ZCRB1-20-GOOR | 20 (40 μL) | 200 μL |
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| TMEM117-ZCRB1-20-GOGO | 20 (40 μL) | 200 μL |
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| TMEM117-ZCRB1-20-GOGR | 20 (40 μL) | 200 μL |
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| TMEM117-ZCRB1-20-GOAQ | 20 (40 μL) | 200 μL |
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| TMEM117-ZCRB1-20-GRRE | 20 (40 μL) | 200 μL |
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| TMEM117-ZCRB1-20-GROR | 20 (40 μL) | 200 μL |
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| TMEM117-ZCRB1-20-GRGO | 20 (40 μL) | 200 μL |
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| TMEM117-ZCRB1-20-GRGR | 20 (40 μL) | 200 μL |
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| TMEM117-ZCRB1-20-GRAQ | 20 (40 μL) | 200 μL |
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| TMEM117-ZCRB1-20-AQRE | 20 (40 μL) | 200 μL |
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| TMEM117-ZCRB1-20-AQOR | 20 (40 μL) | 200 μL |
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| TMEM117-ZCRB1-20-AQGO | 20 (40 μL) | 200 μL |
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| TMEM117-ZCRB1-20-AQGR | 20 (40 μL) | 200 μL |
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| TMEM117-ZCRB1-20-AQAQ | 20 (40 μL) | 200 μL |
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TMEM117 Gene Summary
The Transmembrane Protein 117 (TMEM117) gene is located on chr12 :44229961-44783541 at 12q12.
Gene Name: Transmembrane Protein 117
Chromosome: CHR12: 44229961 -44783541
Locus: 12q12
ZCRB1 Gene Summary
Pre-mRNA splicing is catalyzed by the spliceosome. U12-type spliceosome binds U12-type pre-mRNAs and recognizes the 5' splice site and branch-point sequence. U11 and U12 snRNPs are components of U12-type spliceosome and function as a molecular bridge connecting both ends of the intron. The protein encoded by this gene contains a RNA recognition motif. It was identified as one of the protein components of U11/U12 snRNPs. This protein and many other U11/U12 snRNP proteins are highly conserved in organisms known to contain U12-type introns. These proteins have been shown to be essential for cell viability, suggesting the key roles in U12-type splicing. [provided by RefSeq, Jul 2008]
Gene Name: Zinc Finger CCHC-type And RNA Binding Motif Containing 1
Chromosome: CHR12: 42705887 -42719932
Locus: 12q12
Gene Diseases
The TMEM117 ZCRB1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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