TMEM106A-NMT1 Fusion FISH Probe
The TMEM106A-NMT1 Fusion FISH Probe is used to confirm a fusion of the TMEM106A and NMT1 genes. The fusion of the TMEM106A and NMT1 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TMEM106A-NMT1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TMEM106A-NMT1-20-RERE | 20 (40 μL) | 200 μL |
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| TMEM106A-NMT1-20-REOR | 20 (40 μL) | 200 μL |
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| TMEM106A-NMT1-20-REGO | 20 (40 μL) | 200 μL |
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| TMEM106A-NMT1-20-REGR | 20 (40 μL) | 200 μL |
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| TMEM106A-NMT1-20-REAQ | 20 (40 μL) | 200 μL |
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| TMEM106A-NMT1-20-ORRE | 20 (40 μL) | 200 μL |
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| TMEM106A-NMT1-20-OROR | 20 (40 μL) | 200 μL |
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| TMEM106A-NMT1-20-ORGO | 20 (40 μL) | 200 μL |
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| TMEM106A-NMT1-20-ORAQ | 20 (40 μL) | 200 μL |
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| TMEM106A-NMT1-20-GORE | 20 (40 μL) | 200 μL |
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| TMEM106A-NMT1-20-GOOR | 20 (40 μL) | 200 μL |
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| TMEM106A-NMT1-20-GOGO | 20 (40 μL) | 200 μL |
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| TMEM106A-NMT1-20-GOGR | 20 (40 μL) | 200 μL |
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| TMEM106A-NMT1-20-GOAQ | 20 (40 μL) | 200 μL |
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| TMEM106A-NMT1-20-GRRE | 20 (40 μL) | 200 μL |
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| TMEM106A-NMT1-20-GROR | 20 (40 μL) | 200 μL |
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| TMEM106A-NMT1-20-GRGO | 20 (40 μL) | 200 μL |
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| TMEM106A-NMT1-20-GRGR | 20 (40 μL) | 200 μL |
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| TMEM106A-NMT1-20-GRAQ | 20 (40 μL) | 200 μL |
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| TMEM106A-NMT1-20-AQRE | 20 (40 μL) | 200 μL |
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| TMEM106A-NMT1-20-AQOR | 20 (40 μL) | 200 μL |
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| TMEM106A-NMT1-20-AQGO | 20 (40 μL) | 200 μL |
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| TMEM106A-NMT1-20-AQGR | 20 (40 μL) | 200 μL |
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| TMEM106A-NMT1-20-AQAQ | 20 (40 μL) | 200 μL |
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NMT1 Gene Summary
Myristate, a rare 14-carbon saturated fatty acid, is cotranslationally attached by an amide linkage to the N-terminal glycine residue of cellular and viral proteins with diverse functions. N-myristoyltransferase (NMT; EC 2.3.1.97) catalyzes the transfer of myristate from CoA to proteins. N-myristoylation appears to be irreversible and is required for full expression of the biologic activities of several N-myristoylated proteins, including the alpha subunit of the signal-transducing guanine nucleotide-binding protein (G protein) GO (GNAO1; MIM 139311) (Duronio et al., 1992 [PubMed 1570339]).[supplied by OMIM, Nov 2008]
Gene Name: N-myristoyltransferase 1
Chromosome: CHR17: 43138679 -43186382
Locus: 17q21.31
TMEM106A Gene Summary
The Transmembrane Protein 106A (TMEM106A) gene is located on chr17 :41363893-41371589 at 17q21.31.
Gene Name: Transmembrane Protein 106A
Chromosome: CHR17: 41363893 -41371589
Locus: 17q21.31
Gene Diseases
The TMEM106A NMT1 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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