TLR4-SLC31A1 Fusion FISH Probe
The TLR4-SLC31A1 Fusion FISH Probe is used to confirm a fusion of the TLR4 and SLC31A1 genes. The fusion of the TLR4 and SLC31A1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TLR4-SLC31A1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TLR4-SLC31A1-20-RERE | 20 (40 μL) | 200 μL |
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| TLR4-SLC31A1-20-REOR | 20 (40 μL) | 200 μL |
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| TLR4-SLC31A1-20-REGO | 20 (40 μL) | 200 μL |
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| TLR4-SLC31A1-20-REGR | 20 (40 μL) | 200 μL |
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| TLR4-SLC31A1-20-REAQ | 20 (40 μL) | 200 μL |
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| TLR4-SLC31A1-20-ORRE | 20 (40 μL) | 200 μL |
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| TLR4-SLC31A1-20-OROR | 20 (40 μL) | 200 μL |
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| TLR4-SLC31A1-20-ORGO | 20 (40 μL) | 200 μL |
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| TLR4-SLC31A1-20-ORAQ | 20 (40 μL) | 200 μL |
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| TLR4-SLC31A1-20-GORE | 20 (40 μL) | 200 μL |
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| TLR4-SLC31A1-20-GOOR | 20 (40 μL) | 200 μL |
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| TLR4-SLC31A1-20-GOGO | 20 (40 μL) | 200 μL |
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| TLR4-SLC31A1-20-GOGR | 20 (40 μL) | 200 μL |
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| TLR4-SLC31A1-20-GOAQ | 20 (40 μL) | 200 μL |
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| TLR4-SLC31A1-20-GRRE | 20 (40 μL) | 200 μL |
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| TLR4-SLC31A1-20-GROR | 20 (40 μL) | 200 μL |
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| TLR4-SLC31A1-20-GRGO | 20 (40 μL) | 200 μL |
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| TLR4-SLC31A1-20-GRGR | 20 (40 μL) | 200 μL |
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| TLR4-SLC31A1-20-GRAQ | 20 (40 μL) | 200 μL |
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| TLR4-SLC31A1-20-AQRE | 20 (40 μL) | 200 μL |
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| TLR4-SLC31A1-20-AQOR | 20 (40 μL) | 200 μL |
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| TLR4-SLC31A1-20-AQGO | 20 (40 μL) | 200 μL |
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| TLR4-SLC31A1-20-AQGR | 20 (40 μL) | 200 μL |
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| TLR4-SLC31A1-20-AQAQ | 20 (40 μL) | 200 μL |
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SLC31A1 Gene Summary
The protein encoded by this gene is a high-affinity copper transporter found in the cell membrane. The encoded protein functions as a homotrimer to effect the uptake of dietary copper. [provided by RefSeq, Aug 2011]
Gene Name: Solute Carrier Family 31 Member 1
Chromosome: CHR9: 115983807 -116026772
Locus: 9q32
TLR4 Gene Summary
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
Gene Name: Toll Like Receptor 4
Chromosome: CHR9: 120466459 -120479766
Locus: 9q33.1
Gene Diseases
The TLR4 SLC31A1 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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