TJAP1-ABCC10 Fusion FISH Probe
The TJAP1-ABCC10 Fusion FISH Probe is used to confirm a fusion of the TJAP1 and ABCC10 genes. The fusion of the TJAP1 and ABCC10 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TJAP1-ABCC10-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TJAP1-ABCC10-20-RERE | 20 (40 μL) | 200 μL |
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| TJAP1-ABCC10-20-REOR | 20 (40 μL) | 200 μL |
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| TJAP1-ABCC10-20-REGO | 20 (40 μL) | 200 μL |
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| TJAP1-ABCC10-20-REGR | 20 (40 μL) | 200 μL |
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| TJAP1-ABCC10-20-REAQ | 20 (40 μL) | 200 μL |
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| TJAP1-ABCC10-20-ORRE | 20 (40 μL) | 200 μL |
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| TJAP1-ABCC10-20-OROR | 20 (40 μL) | 200 μL |
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| TJAP1-ABCC10-20-ORGO | 20 (40 μL) | 200 μL |
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| TJAP1-ABCC10-20-ORAQ | 20 (40 μL) | 200 μL |
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| TJAP1-ABCC10-20-GORE | 20 (40 μL) | 200 μL |
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| TJAP1-ABCC10-20-GOOR | 20 (40 μL) | 200 μL |
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| TJAP1-ABCC10-20-GOGO | 20 (40 μL) | 200 μL |
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| TJAP1-ABCC10-20-GOGR | 20 (40 μL) | 200 μL |
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| TJAP1-ABCC10-20-GOAQ | 20 (40 μL) | 200 μL |
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| TJAP1-ABCC10-20-GRRE | 20 (40 μL) | 200 μL |
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| TJAP1-ABCC10-20-GROR | 20 (40 μL) | 200 μL |
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| TJAP1-ABCC10-20-GRGO | 20 (40 μL) | 200 μL |
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| TJAP1-ABCC10-20-GRGR | 20 (40 μL) | 200 μL |
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| TJAP1-ABCC10-20-GRAQ | 20 (40 μL) | 200 μL |
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| TJAP1-ABCC10-20-AQRE | 20 (40 μL) | 200 μL |
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| TJAP1-ABCC10-20-AQOR | 20 (40 μL) | 200 μL |
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| TJAP1-ABCC10-20-AQGO | 20 (40 μL) | 200 μL |
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| TJAP1-ABCC10-20-AQGR | 20 (40 μL) | 200 μL |
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| TJAP1-ABCC10-20-AQAQ | 20 (40 μL) | 200 μL |
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ABCC10 Gene Summary
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This ABC full-transporter is a member of the MRP subfamily which is involved in multi-drug resistance. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2010]
Gene Name: ATP Binding Cassette Subfamily C Member 10
Chromosome: CHR6: 43395291 -43418163
Locus: 6p21.1
TJAP1 Gene Summary
This gene encodes a tight junction-associated protein. Incorporation of the encoded protein into tight junctions occurs at a late stage of formation of the junctions. The encoded protein localizes to the Golgi and may function in vesicle trafficking. Alternatively spliced transcript variants have been described. A related pseudogene exists on the X chromosome. [provided by RefSeq, Mar 2009]
Gene Name: Tight Junction Associated Protein 1
Chromosome: CHR6: 43445260 -43474294
Locus: 6p21.1
Gene Diseases
The TJAP1 ABCC10 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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