TIRAP-FOXRED1 Fusion FISH Probe
The TIRAP-FOXRED1 Fusion FISH Probe is used to confirm a fusion of the TIRAP and FOXRED1 genes. The fusion of the TIRAP and FOXRED1 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TIRAP-FOXRED1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TIRAP-FOXRED1-20-RERE | 20 (40 μL) | 200 μL |
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| TIRAP-FOXRED1-20-REOR | 20 (40 μL) | 200 μL |
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| TIRAP-FOXRED1-20-REGO | 20 (40 μL) | 200 μL |
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| TIRAP-FOXRED1-20-REGR | 20 (40 μL) | 200 μL |
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| TIRAP-FOXRED1-20-REAQ | 20 (40 μL) | 200 μL |
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| TIRAP-FOXRED1-20-ORRE | 20 (40 μL) | 200 μL |
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| TIRAP-FOXRED1-20-OROR | 20 (40 μL) | 200 μL |
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| TIRAP-FOXRED1-20-ORGO | 20 (40 μL) | 200 μL |
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| TIRAP-FOXRED1-20-ORAQ | 20 (40 μL) | 200 μL |
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| TIRAP-FOXRED1-20-GORE | 20 (40 μL) | 200 μL |
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| TIRAP-FOXRED1-20-GOOR | 20 (40 μL) | 200 μL |
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| TIRAP-FOXRED1-20-GOGO | 20 (40 μL) | 200 μL |
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| TIRAP-FOXRED1-20-GOGR | 20 (40 μL) | 200 μL |
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| TIRAP-FOXRED1-20-GOAQ | 20 (40 μL) | 200 μL |
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| TIRAP-FOXRED1-20-GRRE | 20 (40 μL) | 200 μL |
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| TIRAP-FOXRED1-20-GROR | 20 (40 μL) | 200 μL |
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| TIRAP-FOXRED1-20-GRGO | 20 (40 μL) | 200 μL |
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| TIRAP-FOXRED1-20-GRGR | 20 (40 μL) | 200 μL |
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| TIRAP-FOXRED1-20-GRAQ | 20 (40 μL) | 200 μL |
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| TIRAP-FOXRED1-20-AQRE | 20 (40 μL) | 200 μL |
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| TIRAP-FOXRED1-20-AQOR | 20 (40 μL) | 200 μL |
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| TIRAP-FOXRED1-20-AQGO | 20 (40 μL) | 200 μL |
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| TIRAP-FOXRED1-20-AQGR | 20 (40 μL) | 200 μL |
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| TIRAP-FOXRED1-20-AQAQ | 20 (40 μL) | 200 μL |
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FOXRED1 Gene Summary
This gene encodes a protein that contains a FAD-dependent oxidoreductase domain. The encoded protein is localized to the mitochondria and may function as a chaperone protein required for the function of mitochondrial complex I. Mutations in this gene are associated with mitochondrial complex I deficiency. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010]
Gene Name: FAD Dependent Oxidoreductase Domain Containing 1
Chromosome: CHR11: 126138934 -126148027
Locus: 11q24.2
TIRAP Gene Summary
The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008]
Gene Name: TIR Domain Containing Adaptor Protein
Chromosome: CHR11: 126152981 -126164828
Locus: 11q24.2
Gene Diseases
The TIRAP FOXRED1 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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