TIMP2-ANXA1 Fusion FISH Probe
The TIMP2-ANXA1 Fusion FISH Probe is used to confirm a fusion of the TIMP2 and ANXA1 genes. The fusion of the TIMP2 and ANXA1 genes has been associated with Pancreatic Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TIMP2-ANXA1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TIMP2-ANXA1-20-RERE | 20 (40 μL) | 200 μL |
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| TIMP2-ANXA1-20-REOR | 20 (40 μL) | 200 μL |
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| TIMP2-ANXA1-20-REGO | 20 (40 μL) | 200 μL |
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| TIMP2-ANXA1-20-REGR | 20 (40 μL) | 200 μL |
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| TIMP2-ANXA1-20-REAQ | 20 (40 μL) | 200 μL |
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| TIMP2-ANXA1-20-ORRE | 20 (40 μL) | 200 μL |
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| TIMP2-ANXA1-20-OROR | 20 (40 μL) | 200 μL |
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| TIMP2-ANXA1-20-ORGO | 20 (40 μL) | 200 μL |
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| TIMP2-ANXA1-20-ORAQ | 20 (40 μL) | 200 μL |
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| TIMP2-ANXA1-20-GORE | 20 (40 μL) | 200 μL |
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| TIMP2-ANXA1-20-GOOR | 20 (40 μL) | 200 μL |
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| TIMP2-ANXA1-20-GOGO | 20 (40 μL) | 200 μL |
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| TIMP2-ANXA1-20-GOGR | 20 (40 μL) | 200 μL |
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| TIMP2-ANXA1-20-GOAQ | 20 (40 μL) | 200 μL |
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| TIMP2-ANXA1-20-GRRE | 20 (40 μL) | 200 μL |
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| TIMP2-ANXA1-20-GROR | 20 (40 μL) | 200 μL |
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| TIMP2-ANXA1-20-GRGO | 20 (40 μL) | 200 μL |
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| TIMP2-ANXA1-20-GRGR | 20 (40 μL) | 200 μL |
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| TIMP2-ANXA1-20-GRAQ | 20 (40 μL) | 200 μL |
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| TIMP2-ANXA1-20-AQRE | 20 (40 μL) | 200 μL |
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| TIMP2-ANXA1-20-AQOR | 20 (40 μL) | 200 μL |
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| TIMP2-ANXA1-20-AQGO | 20 (40 μL) | 200 μL |
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| TIMP2-ANXA1-20-AQGR | 20 (40 μL) | 200 μL |
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| TIMP2-ANXA1-20-AQAQ | 20 (40 μL) | 200 μL |
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ANXA1 Gene Summary
This gene encodes a membrane-localized protein that binds phospholipids. This protein inhibits phospholipase A2 and has anti-inflammatory activity. Loss of function or expression of this gene has been detected in multiple tumors. [provided by RefSeq, Dec 2014]
Gene Name: Annexin A1
Chromosome: CHR9: 75766780 -75785307
Locus: 9q21.13
TIMP2 Gene Summary
This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix. [provided by RefSeq, Jul 2008]
Gene Name: TIMP Metallopeptidase Inhibitor 2
Chromosome: CHR17: 76849058 -76921472
Locus: 17q25.3
Gene Diseases
The TIMP2 ANXA1 Fusion has been associated with the following diseases:
| Disease Name |
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| Pancreatic Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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