THRAP3-MUTYH Fusion FISH Probe
The THRAP3-MUTYH Fusion FISH Probe is used to confirm a fusion of the THRAP3 and MUTYH genes. The fusion of the THRAP3 and MUTYH genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| THRAP3-MUTYH-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| THRAP3-MUTYH-20-RERE | 20 (40 μL) | 200 μL |
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| THRAP3-MUTYH-20-REOR | 20 (40 μL) | 200 μL |
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| THRAP3-MUTYH-20-REGO | 20 (40 μL) | 200 μL |
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| THRAP3-MUTYH-20-REGR | 20 (40 μL) | 200 μL |
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| THRAP3-MUTYH-20-REAQ | 20 (40 μL) | 200 μL |
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| THRAP3-MUTYH-20-ORRE | 20 (40 μL) | 200 μL |
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| THRAP3-MUTYH-20-OROR | 20 (40 μL) | 200 μL |
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| THRAP3-MUTYH-20-ORGO | 20 (40 μL) | 200 μL |
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| THRAP3-MUTYH-20-ORAQ | 20 (40 μL) | 200 μL |
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| THRAP3-MUTYH-20-GORE | 20 (40 μL) | 200 μL |
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| THRAP3-MUTYH-20-GOOR | 20 (40 μL) | 200 μL |
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| THRAP3-MUTYH-20-GOGO | 20 (40 μL) | 200 μL |
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| THRAP3-MUTYH-20-GOGR | 20 (40 μL) | 200 μL |
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| THRAP3-MUTYH-20-GOAQ | 20 (40 μL) | 200 μL |
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| THRAP3-MUTYH-20-GRRE | 20 (40 μL) | 200 μL |
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| THRAP3-MUTYH-20-GROR | 20 (40 μL) | 200 μL |
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| THRAP3-MUTYH-20-GRGO | 20 (40 μL) | 200 μL |
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| THRAP3-MUTYH-20-GRGR | 20 (40 μL) | 200 μL |
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| THRAP3-MUTYH-20-GRAQ | 20 (40 μL) | 200 μL |
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| THRAP3-MUTYH-20-AQRE | 20 (40 μL) | 200 μL |
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| THRAP3-MUTYH-20-AQOR | 20 (40 μL) | 200 μL |
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| THRAP3-MUTYH-20-AQGO | 20 (40 μL) | 200 μL |
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| THRAP3-MUTYH-20-AQGR | 20 (40 μL) | 200 μL |
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| THRAP3-MUTYH-20-AQAQ | 20 (40 μL) | 200 μL |
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MUTYH Gene Summary
This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. This gene product is thought to play a role in signaling apoptosis by the introduction of single-strand breaks following oxidative damage. Mutations in this gene result in heritable predisposition to colorectal cancer, termed MUTYH-associated polyposis (MAP). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2017]
Gene Name: MutY DNA Glycosylase
Chromosome: CHR1: 45794913 -45806142
Locus: 1p34.1
THRAP3 Gene Summary
The Thyroid Hormone Receptor Associated Protein 3 (THRAP3) gene is located on chr1 :36690016-36770957 at 1p34.3.
Gene Name: Thyroid Hormone Receptor Associated Protein 3
Chromosome: CHR1: 36690016 -36770957
Locus: 1p34.3
Gene Diseases
The THRAP3 MUTYH Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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