THRA-KRT20 Fusion FISH Probe
The THRA-KRT20 Fusion FISH Probe is used to confirm a fusion of the THRA and KRT20 genes. The fusion of the THRA and KRT20 genes has been associated with Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| THRA-KRT20-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| THRA-KRT20-20-RERE | 20 (40 μL) | 200 μL |
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| THRA-KRT20-20-REOR | 20 (40 μL) | 200 μL |
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| THRA-KRT20-20-REGO | 20 (40 μL) | 200 μL |
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| THRA-KRT20-20-REGR | 20 (40 μL) | 200 μL |
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| THRA-KRT20-20-REAQ | 20 (40 μL) | 200 μL |
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| THRA-KRT20-20-ORRE | 20 (40 μL) | 200 μL |
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| THRA-KRT20-20-OROR | 20 (40 μL) | 200 μL |
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| THRA-KRT20-20-ORGO | 20 (40 μL) | 200 μL |
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| THRA-KRT20-20-ORAQ | 20 (40 μL) | 200 μL |
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| THRA-KRT20-20-GORE | 20 (40 μL) | 200 μL |
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| THRA-KRT20-20-GOOR | 20 (40 μL) | 200 μL |
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| THRA-KRT20-20-GOGO | 20 (40 μL) | 200 μL |
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| THRA-KRT20-20-GOGR | 20 (40 μL) | 200 μL |
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| THRA-KRT20-20-GOAQ | 20 (40 μL) | 200 μL |
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| THRA-KRT20-20-GRRE | 20 (40 μL) | 200 μL |
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| THRA-KRT20-20-GROR | 20 (40 μL) | 200 μL |
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| THRA-KRT20-20-GRGO | 20 (40 μL) | 200 μL |
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| THRA-KRT20-20-GRGR | 20 (40 μL) | 200 μL |
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| THRA-KRT20-20-GRAQ | 20 (40 μL) | 200 μL |
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| THRA-KRT20-20-AQRE | 20 (40 μL) | 200 μL |
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| THRA-KRT20-20-AQOR | 20 (40 μL) | 200 μL |
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| THRA-KRT20-20-AQGO | 20 (40 μL) | 200 μL |
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| THRA-KRT20-20-AQGR | 20 (40 μL) | 200 μL |
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| THRA-KRT20-20-AQAQ | 20 (40 μL) | 200 μL |
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THRA Gene Summary
The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Gene Name: Thyroid Hormone Receptor, Alpha
Chromosome: CHR17: 38218445 -38250120
Locus: 17q21.1
KRT20 Gene Summary
The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This cytokeratin is a major cellular protein of mature enterocytes and goblet cells and is specifically expressed in the gastric and intestinal mucosa. The type I cytokeratin genes are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2008]
Gene Name: Keratin 20
Chromosome: CHR17: 39032140 -39041495
Locus: 17q21.2
Gene Diseases
The THRA KRT20 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Carcinosarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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