THADA-IGF2BP3 Fusion FISH Probe
The THADA-IGF2BP3 Fusion FISH Probe is used to confirm a fusion of the THADA and IGF2BP3 genes. The fusion of the THADA and IGF2BP3 genes has been associated with Thyroid Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| THADA-IGF2BP3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| THADA-IGF2BP3-20-RERE | 20 (40 μL) | 200 μL |
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| THADA-IGF2BP3-20-REOR | 20 (40 μL) | 200 μL |
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| THADA-IGF2BP3-20-REGO | 20 (40 μL) | 200 μL |
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| THADA-IGF2BP3-20-REGR | 20 (40 μL) | 200 μL |
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| THADA-IGF2BP3-20-REAQ | 20 (40 μL) | 200 μL |
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| THADA-IGF2BP3-20-ORRE | 20 (40 μL) | 200 μL |
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| THADA-IGF2BP3-20-OROR | 20 (40 μL) | 200 μL |
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| THADA-IGF2BP3-20-ORGO | 20 (40 μL) | 200 μL |
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| THADA-IGF2BP3-20-ORAQ | 20 (40 μL) | 200 μL |
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| THADA-IGF2BP3-20-GORE | 20 (40 μL) | 200 μL |
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| THADA-IGF2BP3-20-GOOR | 20 (40 μL) | 200 μL |
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| THADA-IGF2BP3-20-GOGO | 20 (40 μL) | 200 μL |
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| THADA-IGF2BP3-20-GOGR | 20 (40 μL) | 200 μL |
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| THADA-IGF2BP3-20-GOAQ | 20 (40 μL) | 200 μL |
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| THADA-IGF2BP3-20-GRRE | 20 (40 μL) | 200 μL |
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| THADA-IGF2BP3-20-GROR | 20 (40 μL) | 200 μL |
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| THADA-IGF2BP3-20-GRGO | 20 (40 μL) | 200 μL |
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| THADA-IGF2BP3-20-GRGR | 20 (40 μL) | 200 μL |
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| THADA-IGF2BP3-20-GRAQ | 20 (40 μL) | 200 μL |
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| THADA-IGF2BP3-20-AQRE | 20 (40 μL) | 200 μL |
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| THADA-IGF2BP3-20-AQOR | 20 (40 μL) | 200 μL |
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| THADA-IGF2BP3-20-AQGO | 20 (40 μL) | 200 μL |
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| THADA-IGF2BP3-20-AQGR | 20 (40 μL) | 200 μL |
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| THADA-IGF2BP3-20-AQAQ | 20 (40 μL) | 200 μL |
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IGF2BP3 Gene Summary
The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes. [provided by RefSeq, Jul 2008]
Gene Name: Insulin Like Growth Factor 2 MRNA Binding Protein 3
Chromosome: CHR7: 23349827 -23509995
Locus: 7p15.3
THADA Gene Summary
This gene is the target of 2p21 choromosomal aberrations in benign thyroid adenomas. Single nucleotide polymorphisms (SNPs) in this gene may be associated with type 2 diabetes and polycystic ovary syndrome. The encoded protein is likely involved in the death receptor pathway and apoptosis. [provided by RefSeq, Sep 2016]
Gene Name: THADA, Armadillo Repeat Containing
Chromosome: CHR2: 43457974 -43823185
Locus: 2p21
Gene Diseases
The THADA IGF2BP3 Fusion has been associated with the following diseases:
| Disease Name |
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| Thyroid Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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