TGFBR3-NRD1 Fusion FISH Probe
The TGFBR3-NRD1 Fusion FISH Probe is used to confirm a fusion of the TGFBR3 and NRD1 genes. The fusion of the TGFBR3 and NRD1 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TGFBR3-NRD1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TGFBR3-NRD1-20-RERE | 20 (40 μL) | 200 μL |
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| TGFBR3-NRD1-20-REOR | 20 (40 μL) | 200 μL |
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| TGFBR3-NRD1-20-REGO | 20 (40 μL) | 200 μL |
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| TGFBR3-NRD1-20-REGR | 20 (40 μL) | 200 μL |
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| TGFBR3-NRD1-20-REAQ | 20 (40 μL) | 200 μL |
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| TGFBR3-NRD1-20-ORRE | 20 (40 μL) | 200 μL |
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| TGFBR3-NRD1-20-OROR | 20 (40 μL) | 200 μL |
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| TGFBR3-NRD1-20-ORGO | 20 (40 μL) | 200 μL |
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| TGFBR3-NRD1-20-ORAQ | 20 (40 μL) | 200 μL |
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| TGFBR3-NRD1-20-GORE | 20 (40 μL) | 200 μL |
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| TGFBR3-NRD1-20-GOOR | 20 (40 μL) | 200 μL |
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| TGFBR3-NRD1-20-GOGO | 20 (40 μL) | 200 μL |
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| TGFBR3-NRD1-20-GOGR | 20 (40 μL) | 200 μL |
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| TGFBR3-NRD1-20-GOAQ | 20 (40 μL) | 200 μL |
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| TGFBR3-NRD1-20-GRRE | 20 (40 μL) | 200 μL |
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| TGFBR3-NRD1-20-GROR | 20 (40 μL) | 200 μL |
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| TGFBR3-NRD1-20-GRGO | 20 (40 μL) | 200 μL |
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| TGFBR3-NRD1-20-GRGR | 20 (40 μL) | 200 μL |
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| TGFBR3-NRD1-20-GRAQ | 20 (40 μL) | 200 μL |
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| TGFBR3-NRD1-20-AQRE | 20 (40 μL) | 200 μL |
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| TGFBR3-NRD1-20-AQOR | 20 (40 μL) | 200 μL |
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| TGFBR3-NRD1-20-AQGO | 20 (40 μL) | 200 μL |
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| TGFBR3-NRD1-20-AQGR | 20 (40 μL) | 200 μL |
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| TGFBR3-NRD1-20-AQAQ | 20 (40 μL) | 200 μL |
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TGFBR3 Gene Summary
This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.[provided by RefSeq, Sep 2010]
Gene Name: Transforming Growth Factor Beta Receptor 3
Chromosome: CHR1: 92145899 -92371559
Locus: 1p22.1
Gene Diseases
The TGFBR3 NRD1 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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