TGDS-DAPK1 Fusion FISH Probe
The TGDS-DAPK1 Fusion FISH Probe is used to confirm a fusion of the TGDS and DAPK1 genes. The fusion of the TGDS and DAPK1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TGDS-DAPK1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TGDS-DAPK1-20-RERE | 20 (40 μL) | 200 μL |
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| TGDS-DAPK1-20-REOR | 20 (40 μL) | 200 μL |
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| TGDS-DAPK1-20-REGO | 20 (40 μL) | 200 μL |
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| TGDS-DAPK1-20-REGR | 20 (40 μL) | 200 μL |
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| TGDS-DAPK1-20-REAQ | 20 (40 μL) | 200 μL |
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| TGDS-DAPK1-20-ORRE | 20 (40 μL) | 200 μL |
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| TGDS-DAPK1-20-OROR | 20 (40 μL) | 200 μL |
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| TGDS-DAPK1-20-ORGO | 20 (40 μL) | 200 μL |
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| TGDS-DAPK1-20-ORAQ | 20 (40 μL) | 200 μL |
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| TGDS-DAPK1-20-GORE | 20 (40 μL) | 200 μL |
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| TGDS-DAPK1-20-GOOR | 20 (40 μL) | 200 μL |
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| TGDS-DAPK1-20-GOGO | 20 (40 μL) | 200 μL |
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| TGDS-DAPK1-20-GOGR | 20 (40 μL) | 200 μL |
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| TGDS-DAPK1-20-GOAQ | 20 (40 μL) | 200 μL |
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| TGDS-DAPK1-20-GRRE | 20 (40 μL) | 200 μL |
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| TGDS-DAPK1-20-GROR | 20 (40 μL) | 200 μL |
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| TGDS-DAPK1-20-GRGO | 20 (40 μL) | 200 μL |
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| TGDS-DAPK1-20-GRGR | 20 (40 μL) | 200 μL |
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| TGDS-DAPK1-20-GRAQ | 20 (40 μL) | 200 μL |
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| TGDS-DAPK1-20-AQRE | 20 (40 μL) | 200 μL |
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| TGDS-DAPK1-20-AQOR | 20 (40 μL) | 200 μL |
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| TGDS-DAPK1-20-AQGO | 20 (40 μL) | 200 μL |
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| TGDS-DAPK1-20-AQGR | 20 (40 μL) | 200 μL |
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| TGDS-DAPK1-20-AQAQ | 20 (40 μL) | 200 μL |
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DAPK1 Gene Summary
Death-associated protein kinase 1 is a positive mediator of gamma-interferon induced programmed cell death. DAPK1 encodes a structurally unique 160-kD calmodulin dependent serine-threonine kinase that carries 8 ankyrin repeats and 2 putative P-loop consensus sites. It is a tumor suppressor candidate. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
Gene Name: Death Associated Protein Kinase 1
Chromosome: CHR9: 90112755 -90323549
Locus: 9q21.33
TGDS Gene Summary
The protein encoded by this gene is a member of the short-chain dehydrogenases/reductases (SDR) superfamily, and is thought to contain a nicotinamide adenine dinucleotide (NAD) binding domain. This large SDR family of enzymes is involved in the metabolism of a variety of compounds, including prostaglandins, retinoids, lipids, steroid hormones, and xenobiotics. Mutations in this gene have been associated with Catel-Manzke syndrome, which is characterized by Pierre Robin sequence, and radial deviation of the index finger due to the presence of an accessory bone between the index finger and its proximal phalanx. Pierre Robin sequence is defined by an undersized jaw, backwards displacement of the tongue base that causes an obstruction of the airways, and can also be associated with a cleft palate. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
Gene Name: TDP-glucose 4,6-dehydratase
Chromosome: CHR13: 95226307 -95248511
Locus: 13q32.1
Gene Diseases
The TGDS DAPK1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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