TFR2-NCOR2 Fusion FISH Probe
The TFR2-NCOR2 Fusion FISH Probe is used to confirm a fusion of the TFR2 and NCOR2 genes. The fusion of the TFR2 and NCOR2 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TFR2-NCOR2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| TFR2-NCOR2-20-RERE | 20 (40 μL) | 200 μL |
|
|
| TFR2-NCOR2-20-REOR | 20 (40 μL) | 200 μL |
|
|
| TFR2-NCOR2-20-REGO | 20 (40 μL) | 200 μL |
|
|
| TFR2-NCOR2-20-REGR | 20 (40 μL) | 200 μL |
|
|
| TFR2-NCOR2-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| TFR2-NCOR2-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| TFR2-NCOR2-20-OROR | 20 (40 μL) | 200 μL |
|
|
| TFR2-NCOR2-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| TFR2-NCOR2-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| TFR2-NCOR2-20-GORE | 20 (40 μL) | 200 μL |
|
|
| TFR2-NCOR2-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| TFR2-NCOR2-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| TFR2-NCOR2-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| TFR2-NCOR2-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| TFR2-NCOR2-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| TFR2-NCOR2-20-GROR | 20 (40 μL) | 200 μL |
|
|
| TFR2-NCOR2-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| TFR2-NCOR2-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| TFR2-NCOR2-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| TFR2-NCOR2-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| TFR2-NCOR2-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| TFR2-NCOR2-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| TFR2-NCOR2-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| TFR2-NCOR2-20-AQAQ | 20 (40 μL) | 200 μL |
|
TFR2 Gene Summary
This gene encodes a single-pass type II membrane protein, which is a member of the transferrin receptor-like family. This protein mediates cellular uptake of transferrin-bound iron, and may be involved in iron metabolism, hepatocyte function and erythrocyte differentiation. Mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011]
Gene Name: Transferrin Receptor 2
Chromosome: CHR7: 100218038 -100239173
Locus: 7q22.1
NCOR2 Gene Summary
This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Apr 2011]
Gene Name: Nuclear Receptor Corepressor 2
Chromosome: CHR12: 124808956 -125052010
Locus: 12q24.31
Gene Diseases
The TFR2 NCOR2 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|