TFIP11-AMPD1 Fusion FISH Probe
The TFIP11-AMPD1 Fusion FISH Probe is used to confirm a fusion of the TFIP11 and AMPD1 genes. The fusion of the TFIP11 and AMPD1 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TFIP11-AMPD1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TFIP11-AMPD1-20-RERE | 20 (40 μL) | 200 μL |
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| TFIP11-AMPD1-20-REOR | 20 (40 μL) | 200 μL |
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| TFIP11-AMPD1-20-REGO | 20 (40 μL) | 200 μL |
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| TFIP11-AMPD1-20-REGR | 20 (40 μL) | 200 μL |
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| TFIP11-AMPD1-20-REAQ | 20 (40 μL) | 200 μL |
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| TFIP11-AMPD1-20-ORRE | 20 (40 μL) | 200 μL |
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| TFIP11-AMPD1-20-OROR | 20 (40 μL) | 200 μL |
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| TFIP11-AMPD1-20-ORGO | 20 (40 μL) | 200 μL |
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| TFIP11-AMPD1-20-ORAQ | 20 (40 μL) | 200 μL |
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| TFIP11-AMPD1-20-GORE | 20 (40 μL) | 200 μL |
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| TFIP11-AMPD1-20-GOOR | 20 (40 μL) | 200 μL |
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| TFIP11-AMPD1-20-GOGO | 20 (40 μL) | 200 μL |
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| TFIP11-AMPD1-20-GOGR | 20 (40 μL) | 200 μL |
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| TFIP11-AMPD1-20-GOAQ | 20 (40 μL) | 200 μL |
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| TFIP11-AMPD1-20-GRRE | 20 (40 μL) | 200 μL |
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| TFIP11-AMPD1-20-GROR | 20 (40 μL) | 200 μL |
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| TFIP11-AMPD1-20-GRGO | 20 (40 μL) | 200 μL |
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| TFIP11-AMPD1-20-GRGR | 20 (40 μL) | 200 μL |
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| TFIP11-AMPD1-20-GRAQ | 20 (40 μL) | 200 μL |
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| TFIP11-AMPD1-20-AQRE | 20 (40 μL) | 200 μL |
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| TFIP11-AMPD1-20-AQOR | 20 (40 μL) | 200 μL |
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| TFIP11-AMPD1-20-AQGO | 20 (40 μL) | 200 μL |
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| TFIP11-AMPD1-20-AQGR | 20 (40 μL) | 200 μL |
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| TFIP11-AMPD1-20-AQAQ | 20 (40 μL) | 200 μL |
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AMPD1 Gene Summary
Adenosine monophosphate deaminase 1 catalyzes the deamination of AMP to IMP in skeletal muscle and plays an important role in the purine nucleotide cycle. Two other genes have been identified, AMPD2 and AMPD3, for the liver- and erythocyte-specific isoforms, respectively. Deficiency of the muscle-specific enzyme is apparently a common cause of exercise-induced myopathy and probably the most common cause of metabolic myopathy in the human. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010]
Gene Name: Adenosine Monophosphate Deaminase 1
Chromosome: CHR1: 115215719 -115238239
Locus: 1p13.2
TFIP11 Gene Summary
This gene encodes a protein component of the spliceosome that promotes the release of the lariat-intron during late-stage splicing through the recruitment of a pre-mRNA splicing factor called DEAH-box helicase 15. The encoded protein contains a G-patch domain, a hallmark of RNA-processing proteins, that binds DEAH-box helicase 15. This protein contains an atypical nuclear localization sequence as well as a nuclear speckle-targeting sequence, enabling it to localize to distinct speckled regions within the cell nucleus. Polymorphisms in this gene are associated with dental caries suggesting a role in amelogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016]
Gene Name: Tuftelin Interacting Protein 11
Chromosome: CHR22: 26887893 -26908437
Locus: 22q12.1
Gene Diseases
The TFIP11 AMPD1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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