TFF1-DDX21 Fusion FISH Probe
The TFF1-DDX21 Fusion FISH Probe is used to confirm a fusion of the TFF1 and DDX21 genes. The fusion of the TFF1 and DDX21 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TFF1-DDX21-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TFF1-DDX21-20-RERE | 20 (40 μL) | 200 μL |
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| TFF1-DDX21-20-REOR | 20 (40 μL) | 200 μL |
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| TFF1-DDX21-20-REGO | 20 (40 μL) | 200 μL |
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| TFF1-DDX21-20-REGR | 20 (40 μL) | 200 μL |
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| TFF1-DDX21-20-REAQ | 20 (40 μL) | 200 μL |
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| TFF1-DDX21-20-ORRE | 20 (40 μL) | 200 μL |
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| TFF1-DDX21-20-OROR | 20 (40 μL) | 200 μL |
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| TFF1-DDX21-20-ORGO | 20 (40 μL) | 200 μL |
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| TFF1-DDX21-20-ORAQ | 20 (40 μL) | 200 μL |
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| TFF1-DDX21-20-GORE | 20 (40 μL) | 200 μL |
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| TFF1-DDX21-20-GOOR | 20 (40 μL) | 200 μL |
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| TFF1-DDX21-20-GOGO | 20 (40 μL) | 200 μL |
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| TFF1-DDX21-20-GOGR | 20 (40 μL) | 200 μL |
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| TFF1-DDX21-20-GOAQ | 20 (40 μL) | 200 μL |
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| TFF1-DDX21-20-GRRE | 20 (40 μL) | 200 μL |
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| TFF1-DDX21-20-GROR | 20 (40 μL) | 200 μL |
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| TFF1-DDX21-20-GRGO | 20 (40 μL) | 200 μL |
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| TFF1-DDX21-20-GRGR | 20 (40 μL) | 200 μL |
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| TFF1-DDX21-20-GRAQ | 20 (40 μL) | 200 μL |
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| TFF1-DDX21-20-AQRE | 20 (40 μL) | 200 μL |
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| TFF1-DDX21-20-AQOR | 20 (40 μL) | 200 μL |
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| TFF1-DDX21-20-AQGO | 20 (40 μL) | 200 μL |
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| TFF1-DDX21-20-AQGR | 20 (40 μL) | 200 μL |
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| TFF1-DDX21-20-AQAQ | 20 (40 μL) | 200 μL |
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TFF1 Gene Summary
Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq, Jul 2008]
Gene Name: Trefoil Factor 1
Chromosome: CHR21: 43782390 -43786644
Locus: 21q22.3
DDX21 Gene Summary
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an antigen recognized by autoimmune antibodies from a patient with watermelon stomach disease. This protein unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription. [provided by RefSeq, Jul 2008]
Gene Name: DExD-box Helicase 21
Chromosome: CHR10: 70715891 -70744279
Locus: 10q22.1
Gene Diseases
The TFF1 DDX21 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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