TFEB-PGC Fusion FISH Probe
The TFEB-PGC Fusion FISH Probe is used to confirm a fusion of the TFEB and PGC genes. The fusion of the TFEB and PGC genes has been associated with Ovarian Serous Cystadenocarcinoma, and Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TFEB-PGC-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TFEB-PGC-20-RERE | 20 (40 μL) | 200 μL |
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| TFEB-PGC-20-REOR | 20 (40 μL) | 200 μL |
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| TFEB-PGC-20-REGO | 20 (40 μL) | 200 μL |
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| TFEB-PGC-20-REGR | 20 (40 μL) | 200 μL |
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| TFEB-PGC-20-REAQ | 20 (40 μL) | 200 μL |
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| TFEB-PGC-20-ORRE | 20 (40 μL) | 200 μL |
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| TFEB-PGC-20-OROR | 20 (40 μL) | 200 μL |
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| TFEB-PGC-20-ORGO | 20 (40 μL) | 200 μL |
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| TFEB-PGC-20-ORAQ | 20 (40 μL) | 200 μL |
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| TFEB-PGC-20-GORE | 20 (40 μL) | 200 μL |
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| TFEB-PGC-20-GOOR | 20 (40 μL) | 200 μL |
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| TFEB-PGC-20-GOGO | 20 (40 μL) | 200 μL |
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| TFEB-PGC-20-GOGR | 20 (40 μL) | 200 μL |
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| TFEB-PGC-20-GOAQ | 20 (40 μL) | 200 μL |
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| TFEB-PGC-20-GRRE | 20 (40 μL) | 200 μL |
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| TFEB-PGC-20-GROR | 20 (40 μL) | 200 μL |
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| TFEB-PGC-20-GRGO | 20 (40 μL) | 200 μL |
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| TFEB-PGC-20-GRGR | 20 (40 μL) | 200 μL |
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| TFEB-PGC-20-GRAQ | 20 (40 μL) | 200 μL |
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| TFEB-PGC-20-AQRE | 20 (40 μL) | 200 μL |
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| TFEB-PGC-20-AQOR | 20 (40 μL) | 200 μL |
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| TFEB-PGC-20-AQGO | 20 (40 μL) | 200 μL |
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| TFEB-PGC-20-AQGR | 20 (40 μL) | 200 μL |
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| TFEB-PGC-20-AQAQ | 20 (40 μL) | 200 μL |
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PGC Gene Summary
This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Oct 2009]
Gene Name: Progastricsin
Chromosome: CHR6: 41704448 -41715139
Locus: 6p21.1
TFEB Gene Summary
The Transcription Factor EB (TFEB) gene is located on chr6 :41651715-41703997 at 6p21.1.
Gene Name: Transcription Factor EB
Chromosome: CHR6: 41651715 -41703997
Locus: 6p21.1
Gene Diseases
The TFEB PGC Fusion has been associated with the following diseases:
| Disease Name |
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| Ovarian Serous Cystadenocarcinoma |
| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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