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TFE3-SFPQ Fusion FISH Probe

The TFE3-SFPQ Fusion FISH Probe is used to confirm a fusion of the TFE3 and SFPQ genes. The fusion of the TFE3 and SFPQ genes has been associated with Kidney Renal Clear Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
TFE3-SFPQ-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
TFE3-SFPQ-20-RERE 20 (40 μL) 200 μL
TFE3-SFPQ-20-REOR 20 (40 μL) 200 μL
TFE3-SFPQ-20-REGO 20 (40 μL) 200 μL
TFE3-SFPQ-20-REGR 20 (40 μL) 200 μL
TFE3-SFPQ-20-REAQ 20 (40 μL) 200 μL
TFE3-SFPQ-20-ORRE 20 (40 μL) 200 μL
TFE3-SFPQ-20-OROR 20 (40 μL) 200 μL
TFE3-SFPQ-20-ORGO 20 (40 μL) 200 μL
TFE3-SFPQ-20-ORAQ 20 (40 μL) 200 μL
TFE3-SFPQ-20-GORE 20 (40 μL) 200 μL
TFE3-SFPQ-20-GOOR 20 (40 μL) 200 μL
TFE3-SFPQ-20-GOGO 20 (40 μL) 200 μL
TFE3-SFPQ-20-GOGR 20 (40 μL) 200 μL
TFE3-SFPQ-20-GOAQ 20 (40 μL) 200 μL
TFE3-SFPQ-20-GRRE 20 (40 μL) 200 μL
TFE3-SFPQ-20-GROR 20 (40 μL) 200 μL
TFE3-SFPQ-20-GRGO 20 (40 μL) 200 μL
TFE3-SFPQ-20-GRGR 20 (40 μL) 200 μL
TFE3-SFPQ-20-GRAQ 20 (40 μL) 200 μL
TFE3-SFPQ-20-AQRE 20 (40 μL) 200 μL
TFE3-SFPQ-20-AQOR 20 (40 μL) 200 μL
TFE3-SFPQ-20-AQGO 20 (40 μL) 200 μL
TFE3-SFPQ-20-AQGR 20 (40 μL) 200 μL
TFE3-SFPQ-20-AQAQ 20 (40 μL) 200 μL

SFPQ Gene Summary

The Splicing Factor Proline And Glutamine Rich (SFPQ) gene is located on chr1 :35649200-35658743 at 1p34.3.

Gene Name: Splicing Factor Proline And Glutamine Rich

Chromosome: CHR1: 35649200 -35658743

Locus: 1p34.3

TFE3 Gene Summary

This gene encodes a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences in the promoter of genes. The encoded protein promotes the expression of genes downstream of transforming growth factor beta (TGF-beta) signaling. This gene may be involved in chromosomal translocations in renal cell carcinomas and other cancers, resulting in the production of fusion proteins. Translocation partners include PRCC (papillary renal cell carcinoma), NONO (non-POU domain containing, octamer-binding), and ASPSCR1 (alveolar soft part sarcoma chromosome region, candidate 1), among other genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

Gene Name: Transcription Factor Binding To IGHM Enhancer 3

Chromosome: CHRX: 48886241 -48900990

Locus: Xp11.23

Gene Diseases

The TFE3 SFPQ Fusion has been associated with the following diseases:

Disease Name
Kidney Renal Clear Cell Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.