TFDP1-CUL4A Fusion FISH Probe
The TFDP1-CUL4A Fusion FISH Probe is used to confirm a fusion of the TFDP1 and CUL4A genes. The fusion of the TFDP1 and CUL4A genes has been associated with Lung Adenocarcinoma, and Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TFDP1-CUL4A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TFDP1-CUL4A-20-RERE | 20 (40 μL) | 200 μL |
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| TFDP1-CUL4A-20-REOR | 20 (40 μL) | 200 μL |
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| TFDP1-CUL4A-20-REGO | 20 (40 μL) | 200 μL |
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| TFDP1-CUL4A-20-REGR | 20 (40 μL) | 200 μL |
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| TFDP1-CUL4A-20-REAQ | 20 (40 μL) | 200 μL |
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| TFDP1-CUL4A-20-ORRE | 20 (40 μL) | 200 μL |
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| TFDP1-CUL4A-20-OROR | 20 (40 μL) | 200 μL |
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| TFDP1-CUL4A-20-ORGO | 20 (40 μL) | 200 μL |
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| TFDP1-CUL4A-20-ORAQ | 20 (40 μL) | 200 μL |
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| TFDP1-CUL4A-20-GORE | 20 (40 μL) | 200 μL |
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| TFDP1-CUL4A-20-GOOR | 20 (40 μL) | 200 μL |
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| TFDP1-CUL4A-20-GOGO | 20 (40 μL) | 200 μL |
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| TFDP1-CUL4A-20-GOGR | 20 (40 μL) | 200 μL |
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| TFDP1-CUL4A-20-GOAQ | 20 (40 μL) | 200 μL |
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| TFDP1-CUL4A-20-GRRE | 20 (40 μL) | 200 μL |
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| TFDP1-CUL4A-20-GROR | 20 (40 μL) | 200 μL |
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| TFDP1-CUL4A-20-GRGO | 20 (40 μL) | 200 μL |
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| TFDP1-CUL4A-20-GRGR | 20 (40 μL) | 200 μL |
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| TFDP1-CUL4A-20-GRAQ | 20 (40 μL) | 200 μL |
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| TFDP1-CUL4A-20-AQRE | 20 (40 μL) | 200 μL |
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| TFDP1-CUL4A-20-AQOR | 20 (40 μL) | 200 μL |
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| TFDP1-CUL4A-20-AQGO | 20 (40 μL) | 200 μL |
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| TFDP1-CUL4A-20-AQGR | 20 (40 μL) | 200 μL |
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| TFDP1-CUL4A-20-AQAQ | 20 (40 μL) | 200 μL |
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TFDP1 Gene Summary
This gene encodes a member of a family of transcription factors that heterodimerize with E2F proteins to enhance their DNA-binding activity and promote transcription from E2F target genes. The encoded protein functions as part of this complex to control the transcriptional activity of numerous genes involved in cell cycle progression from G1 to S phase. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1, 15, and X.[provided by RefSeq, Jan 2009]
Gene Name: Transcription Factor Dp-1
Chromosome: CHR13: 114239002 -114295788
Locus: 13q34
CUL4A Gene Summary
CUL4A is the ubiquitin ligase component of a multimeric complex involved in the degradation of DNA damage-response proteins (Liu et al., 2009 [PubMed 19481525]).[supplied by OMIM, Oct 2009]
Gene Name: Cullin 4A
Chromosome: CHR13: 113863085 -113919392
Locus: 13q34
Gene Diseases
The TFDP1 CUL4A Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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