TF-UTRN Fusion FISH Probe
The TF-UTRN Fusion FISH Probe is used to confirm a fusion of the TF and UTRN genes. The fusion of the TF and UTRN genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TF-UTRN-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TF-UTRN-20-RERE | 20 (40 μL) | 200 μL |
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| TF-UTRN-20-REOR | 20 (40 μL) | 200 μL |
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| TF-UTRN-20-REGO | 20 (40 μL) | 200 μL |
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| TF-UTRN-20-REGR | 20 (40 μL) | 200 μL |
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| TF-UTRN-20-REAQ | 20 (40 μL) | 200 μL |
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| TF-UTRN-20-ORRE | 20 (40 μL) | 200 μL |
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| TF-UTRN-20-OROR | 20 (40 μL) | 200 μL |
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| TF-UTRN-20-ORGO | 20 (40 μL) | 200 μL |
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| TF-UTRN-20-ORAQ | 20 (40 μL) | 200 μL |
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| TF-UTRN-20-GORE | 20 (40 μL) | 200 μL |
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| TF-UTRN-20-GOOR | 20 (40 μL) | 200 μL |
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| TF-UTRN-20-GOGO | 20 (40 μL) | 200 μL |
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| TF-UTRN-20-GOGR | 20 (40 μL) | 200 μL |
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| TF-UTRN-20-GOAQ | 20 (40 μL) | 200 μL |
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| TF-UTRN-20-GRRE | 20 (40 μL) | 200 μL |
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| TF-UTRN-20-GROR | 20 (40 μL) | 200 μL |
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| TF-UTRN-20-GRGO | 20 (40 μL) | 200 μL |
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| TF-UTRN-20-GRGR | 20 (40 μL) | 200 μL |
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| TF-UTRN-20-GRAQ | 20 (40 μL) | 200 μL |
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| TF-UTRN-20-AQRE | 20 (40 μL) | 200 μL |
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| TF-UTRN-20-AQOR | 20 (40 μL) | 200 μL |
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| TF-UTRN-20-AQGO | 20 (40 μL) | 200 μL |
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| TF-UTRN-20-AQGR | 20 (40 μL) | 200 μL |
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| TF-UTRN-20-AQAQ | 20 (40 μL) | 200 μL |
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TF Gene Summary
This gene encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum. [provided by RefSeq, Sep 2009]
Gene Name: Transferrin
Chromosome: CHR3: 133464976 -133497850
Locus: 3q22.1
UTRN Gene Summary
This gene shares both structural and functional similarities with the dystrophin gene. It contains an actin-binding N-terminus, a triple coiled-coil repeat central region, and a C-terminus that consists of protein-protein interaction motifs which interact with dystroglycan protein components. The protein encoded by this gene is located at the neuromuscular synapse and myotendinous junctions, where it participates in post-synaptic membrane maintenance and acetylcholine receptor clustering. Mouse studies suggest that this gene may serve as a functional substitute for the dystrophin gene and therefore, may serve as a potential therapeutic alternative to muscular dystrophy which is caused by mutations in the dystrophin gene. Alternative splicing of the utrophin gene has been described; however, the full-length nature of these variants has not yet been determined. [provided by RefSeq, Jul 2008]
Gene Name: Utrophin
Chromosome: CHR6: 144612872 -145174170
Locus: 6q24.2
Gene Diseases
The TF UTRN Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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