TF-CCT5 Fusion FISH Probe
The TF-CCT5 Fusion FISH Probe is used to confirm a fusion of the TF and CCT5 genes. The fusion of the TF and CCT5 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TF-CCT5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TF-CCT5-20-RERE | 20 (40 μL) | 200 μL |
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| TF-CCT5-20-REOR | 20 (40 μL) | 200 μL |
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| TF-CCT5-20-REGO | 20 (40 μL) | 200 μL |
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| TF-CCT5-20-REGR | 20 (40 μL) | 200 μL |
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| TF-CCT5-20-REAQ | 20 (40 μL) | 200 μL |
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| TF-CCT5-20-ORRE | 20 (40 μL) | 200 μL |
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| TF-CCT5-20-OROR | 20 (40 μL) | 200 μL |
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| TF-CCT5-20-ORGO | 20 (40 μL) | 200 μL |
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| TF-CCT5-20-ORAQ | 20 (40 μL) | 200 μL |
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| TF-CCT5-20-GORE | 20 (40 μL) | 200 μL |
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| TF-CCT5-20-GOOR | 20 (40 μL) | 200 μL |
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| TF-CCT5-20-GOGO | 20 (40 μL) | 200 μL |
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| TF-CCT5-20-GOGR | 20 (40 μL) | 200 μL |
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| TF-CCT5-20-GOAQ | 20 (40 μL) | 200 μL |
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| TF-CCT5-20-GRRE | 20 (40 μL) | 200 μL |
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| TF-CCT5-20-GROR | 20 (40 μL) | 200 μL |
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| TF-CCT5-20-GRGO | 20 (40 μL) | 200 μL |
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| TF-CCT5-20-GRGR | 20 (40 μL) | 200 μL |
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| TF-CCT5-20-GRAQ | 20 (40 μL) | 200 μL |
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| TF-CCT5-20-AQRE | 20 (40 μL) | 200 μL |
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| TF-CCT5-20-AQOR | 20 (40 μL) | 200 μL |
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| TF-CCT5-20-AQGO | 20 (40 μL) | 200 μL |
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| TF-CCT5-20-AQGR | 20 (40 μL) | 200 μL |
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| TF-CCT5-20-AQAQ | 20 (40 μL) | 200 μL |
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TF Gene Summary
This gene encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum. [provided by RefSeq, Sep 2009]
Gene Name: Transferrin
Chromosome: CHR3: 133464976 -133497850
Locus: 3q22.1
CCT5 Gene Summary
The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Mutations in this gene cause hereditary sensory and autonomic neuropathy with spastic paraplegia (HSNSP). Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 13. [provided by RefSeq, Apr 2015]
Gene Name: Chaperonin Containing TCP1 Subunit 5
Chromosome: CHR5: 10250281 -10266501
Locus: 5p15.2
Gene Diseases
The TF CCT5 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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