TF-ARFGEF2 Fusion FISH Probe
The TF-ARFGEF2 Fusion FISH Probe is used to confirm a fusion of the TF and ARFGEF2 genes. The fusion of the TF and ARFGEF2 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TF-ARFGEF2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TF-ARFGEF2-20-RERE | 20 (40 μL) | 200 μL |
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| TF-ARFGEF2-20-REOR | 20 (40 μL) | 200 μL |
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| TF-ARFGEF2-20-REGO | 20 (40 μL) | 200 μL |
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| TF-ARFGEF2-20-REGR | 20 (40 μL) | 200 μL |
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| TF-ARFGEF2-20-REAQ | 20 (40 μL) | 200 μL |
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| TF-ARFGEF2-20-ORRE | 20 (40 μL) | 200 μL |
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| TF-ARFGEF2-20-OROR | 20 (40 μL) | 200 μL |
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| TF-ARFGEF2-20-ORGO | 20 (40 μL) | 200 μL |
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| TF-ARFGEF2-20-ORAQ | 20 (40 μL) | 200 μL |
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| TF-ARFGEF2-20-GORE | 20 (40 μL) | 200 μL |
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| TF-ARFGEF2-20-GOOR | 20 (40 μL) | 200 μL |
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| TF-ARFGEF2-20-GOGO | 20 (40 μL) | 200 μL |
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| TF-ARFGEF2-20-GOGR | 20 (40 μL) | 200 μL |
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| TF-ARFGEF2-20-GOAQ | 20 (40 μL) | 200 μL |
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| TF-ARFGEF2-20-GRRE | 20 (40 μL) | 200 μL |
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| TF-ARFGEF2-20-GROR | 20 (40 μL) | 200 μL |
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| TF-ARFGEF2-20-GRGO | 20 (40 μL) | 200 μL |
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| TF-ARFGEF2-20-GRGR | 20 (40 μL) | 200 μL |
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| TF-ARFGEF2-20-GRAQ | 20 (40 μL) | 200 μL |
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| TF-ARFGEF2-20-AQRE | 20 (40 μL) | 200 μL |
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| TF-ARFGEF2-20-AQOR | 20 (40 μL) | 200 μL |
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| TF-ARFGEF2-20-AQGO | 20 (40 μL) | 200 μL |
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| TF-ARFGEF2-20-AQGR | 20 (40 μL) | 200 μL |
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| TF-ARFGEF2-20-AQAQ | 20 (40 μL) | 200 μL |
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TF Gene Summary
This gene encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum. [provided by RefSeq, Sep 2009]
Gene Name: Transferrin
Chromosome: CHR3: 133464976 -133497850
Locus: 3q22.1
ARFGEF2 Gene Summary
ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP and is involved in Golgi transport. It contains a Sec7 domain, which may be responsible for its guanine-nucleotide exchange activity and also brefeldin A inhibition. [provided by RefSeq, Jul 2008]
Gene Name: ADP Ribosylation Factor Guanine Nucleotide Exchange Factor 2
Chromosome: CHR20: 47538274 -47653230
Locus: 20q13.13
Gene Diseases
The TF ARFGEF2 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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