TET3-DGUOK Fusion FISH Probe
The TET3-DGUOK Fusion FISH Probe is used to confirm a fusion of the TET3 and DGUOK genes. The fusion of the TET3 and DGUOK genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TET3-DGUOK-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TET3-DGUOK-20-RERE | 20 (40 μL) | 200 μL |
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| TET3-DGUOK-20-REOR | 20 (40 μL) | 200 μL |
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| TET3-DGUOK-20-REGO | 20 (40 μL) | 200 μL |
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| TET3-DGUOK-20-REGR | 20 (40 μL) | 200 μL |
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| TET3-DGUOK-20-REAQ | 20 (40 μL) | 200 μL |
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| TET3-DGUOK-20-ORRE | 20 (40 μL) | 200 μL |
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| TET3-DGUOK-20-OROR | 20 (40 μL) | 200 μL |
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| TET3-DGUOK-20-ORGO | 20 (40 μL) | 200 μL |
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| TET3-DGUOK-20-ORAQ | 20 (40 μL) | 200 μL |
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| TET3-DGUOK-20-GORE | 20 (40 μL) | 200 μL |
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| TET3-DGUOK-20-GOOR | 20 (40 μL) | 200 μL |
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| TET3-DGUOK-20-GOGO | 20 (40 μL) | 200 μL |
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| TET3-DGUOK-20-GOGR | 20 (40 μL) | 200 μL |
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| TET3-DGUOK-20-GOAQ | 20 (40 μL) | 200 μL |
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| TET3-DGUOK-20-GRRE | 20 (40 μL) | 200 μL |
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| TET3-DGUOK-20-GROR | 20 (40 μL) | 200 μL |
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| TET3-DGUOK-20-GRGO | 20 (40 μL) | 200 μL |
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| TET3-DGUOK-20-GRGR | 20 (40 μL) | 200 μL |
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| TET3-DGUOK-20-GRAQ | 20 (40 μL) | 200 μL |
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| TET3-DGUOK-20-AQRE | 20 (40 μL) | 200 μL |
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| TET3-DGUOK-20-AQOR | 20 (40 μL) | 200 μL |
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| TET3-DGUOK-20-AQGO | 20 (40 μL) | 200 μL |
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| TET3-DGUOK-20-AQGR | 20 (40 μL) | 200 μL |
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| TET3-DGUOK-20-AQAQ | 20 (40 μL) | 200 μL |
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DGUOK Gene Summary
In mammalian cells, the phosphorylation of purine deoxyribonucleosides is mediated predominantly by two deoxyribonucleoside kinases, cytosolic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. The protein encoded by this gene is responsible for phosphorylation of purine deoxyribonucleosides in the mitochondrial matrix. In addition, this protein phosphorylates several purine deoxyribonucleoside analogs used in the treatment of lymphoproliferative disorders, and this phosphorylation is critical for the effectiveness of the analogs. Alternative splice variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Deoxyguanosine Kinase
Chromosome: CHR2: 74153952 -74186088
Locus: 2p13.1
TET3 Gene Summary
Members of the ten-eleven translocation (TET) gene family, including TET3, play a role in the DNA methylation process (Langemeijer et al., 2009 [PubMed 19923888]).[supplied by OMIM, Nov 2010]
Gene Name: Tet Methylcytosine Dioxygenase 3
Chromosome: CHR2: 74273449 -74335302
Locus: 2p13.1
Gene Diseases
The TET3 DGUOK Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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