TET2-ADH6 Fusion FISH Probe
The TET2-ADH6 Fusion FISH Probe is used to confirm a fusion of the TET2 and ADH6 genes. The fusion of the TET2 and ADH6 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TET2-ADH6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TET2-ADH6-20-RERE | 20 (40 μL) | 200 μL |
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| TET2-ADH6-20-REOR | 20 (40 μL) | 200 μL |
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| TET2-ADH6-20-REGO | 20 (40 μL) | 200 μL |
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| TET2-ADH6-20-REGR | 20 (40 μL) | 200 μL |
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| TET2-ADH6-20-REAQ | 20 (40 μL) | 200 μL |
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| TET2-ADH6-20-ORRE | 20 (40 μL) | 200 μL |
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| TET2-ADH6-20-OROR | 20 (40 μL) | 200 μL |
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| TET2-ADH6-20-ORGO | 20 (40 μL) | 200 μL |
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| TET2-ADH6-20-ORAQ | 20 (40 μL) | 200 μL |
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| TET2-ADH6-20-GORE | 20 (40 μL) | 200 μL |
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| TET2-ADH6-20-GOOR | 20 (40 μL) | 200 μL |
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| TET2-ADH6-20-GOGO | 20 (40 μL) | 200 μL |
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| TET2-ADH6-20-GOGR | 20 (40 μL) | 200 μL |
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| TET2-ADH6-20-GOAQ | 20 (40 μL) | 200 μL |
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| TET2-ADH6-20-GRRE | 20 (40 μL) | 200 μL |
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| TET2-ADH6-20-GROR | 20 (40 μL) | 200 μL |
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| TET2-ADH6-20-GRGO | 20 (40 μL) | 200 μL |
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| TET2-ADH6-20-GRGR | 20 (40 μL) | 200 μL |
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| TET2-ADH6-20-GRAQ | 20 (40 μL) | 200 μL |
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| TET2-ADH6-20-AQRE | 20 (40 μL) | 200 μL |
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| TET2-ADH6-20-AQOR | 20 (40 μL) | 200 μL |
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| TET2-ADH6-20-AQGO | 20 (40 μL) | 200 μL |
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| TET2-ADH6-20-AQGR | 20 (40 μL) | 200 μL |
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| TET2-ADH6-20-AQAQ | 20 (40 μL) | 200 μL |
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ADH6 Gene Summary
This gene encodes class V alcohol dehydrogenase, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This gene is expressed in the stomach as well as in the liver, and it contains a glucocorticoid response element upstream of its 5' UTR, which is a steroid hormone receptor binding site. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Alcohol Dehydrogenase 6 (class V)
Chromosome: CHR4: 100123794 -100140403
Locus: 4q23
TET2 Gene Summary
The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defects in this gene have been associated with several myeloproliferative disorders. Two variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
Gene Name: Tet Methylcytosine Dioxygenase 2
Chromosome: CHR4: 106067841 -106200960
Locus: 4q24
Gene Diseases
The TET2 ADH6 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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