TERF2IP-CKLF Fusion FISH Probe
The TERF2IP-CKLF Fusion FISH Probe is used to confirm a fusion of the TERF2IP and CKLF genes. The fusion of the TERF2IP and CKLF genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TERF2IP-CKLF-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TERF2IP-CKLF-20-RERE | 20 (40 μL) | 200 μL |
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| TERF2IP-CKLF-20-REOR | 20 (40 μL) | 200 μL |
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| TERF2IP-CKLF-20-REGO | 20 (40 μL) | 200 μL |
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| TERF2IP-CKLF-20-REGR | 20 (40 μL) | 200 μL |
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| TERF2IP-CKLF-20-REAQ | 20 (40 μL) | 200 μL |
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| TERF2IP-CKLF-20-ORRE | 20 (40 μL) | 200 μL |
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| TERF2IP-CKLF-20-OROR | 20 (40 μL) | 200 μL |
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| TERF2IP-CKLF-20-ORGO | 20 (40 μL) | 200 μL |
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| TERF2IP-CKLF-20-ORAQ | 20 (40 μL) | 200 μL |
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| TERF2IP-CKLF-20-GORE | 20 (40 μL) | 200 μL |
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| TERF2IP-CKLF-20-GOOR | 20 (40 μL) | 200 μL |
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| TERF2IP-CKLF-20-GOGO | 20 (40 μL) | 200 μL |
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| TERF2IP-CKLF-20-GOGR | 20 (40 μL) | 200 μL |
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| TERF2IP-CKLF-20-GOAQ | 20 (40 μL) | 200 μL |
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| TERF2IP-CKLF-20-GRRE | 20 (40 μL) | 200 μL |
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| TERF2IP-CKLF-20-GROR | 20 (40 μL) | 200 μL |
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| TERF2IP-CKLF-20-GRGO | 20 (40 μL) | 200 μL |
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| TERF2IP-CKLF-20-GRGR | 20 (40 μL) | 200 μL |
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| TERF2IP-CKLF-20-GRAQ | 20 (40 μL) | 200 μL |
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| TERF2IP-CKLF-20-AQRE | 20 (40 μL) | 200 μL |
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| TERF2IP-CKLF-20-AQOR | 20 (40 μL) | 200 μL |
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| TERF2IP-CKLF-20-AQGO | 20 (40 μL) | 200 μL |
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| TERF2IP-CKLF-20-AQGR | 20 (40 μL) | 200 μL |
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| TERF2IP-CKLF-20-AQAQ | 20 (40 μL) | 200 μL |
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CKLF Gene Summary
The product of this gene is a cytokine. Cytokines are small proteins that have an essential role in the immune and inflammatory responses. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 16. The protein encoded by this gene is a potent chemoattractant for neutrophils, monocytes and lymphocytes. It also can stimulate the proliferation of skeletal muscle cells. This protein may play important roles in inflammation and in the regeneration of skeletal muscle. Alternatively spliced transcript variants encoding different isoforms have been identified. Naturally occurring read-through transcription occurs between this locus and the neighboring locus CMTM1 (CKLF-like MARVEL transmembrane domain containing 1).[provided by RefSeq, Feb 2011]
Gene Name: Chemokine Like Factor
Chromosome: CHR16: 66586465 -66600190
Locus: 16q21
TERF2IP Gene Summary
The gene encodes a protein that is part of a complex involved in telomere length regulation. Pseudogenes are present on chromosomes 5 and 22. [provided by RefSeq, Apr 2010]
Gene Name: TERF2 Interacting Protein
Chromosome: CHR16: 75681634 -75691341
Locus: 16q23.1
Gene Diseases
The TERF2IP CKLF Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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