TEF-KIF26B Fusion FISH Probe
The TEF-KIF26B Fusion FISH Probe is used to confirm a fusion of the TEF and KIF26B genes. The fusion of the TEF and KIF26B genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TEF-KIF26B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TEF-KIF26B-20-RERE | 20 (40 μL) | 200 μL |
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| TEF-KIF26B-20-REOR | 20 (40 μL) | 200 μL |
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| TEF-KIF26B-20-REGO | 20 (40 μL) | 200 μL |
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| TEF-KIF26B-20-REGR | 20 (40 μL) | 200 μL |
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| TEF-KIF26B-20-REAQ | 20 (40 μL) | 200 μL |
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| TEF-KIF26B-20-ORRE | 20 (40 μL) | 200 μL |
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| TEF-KIF26B-20-OROR | 20 (40 μL) | 200 μL |
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| TEF-KIF26B-20-ORGO | 20 (40 μL) | 200 μL |
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| TEF-KIF26B-20-ORAQ | 20 (40 μL) | 200 μL |
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| TEF-KIF26B-20-GORE | 20 (40 μL) | 200 μL |
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| TEF-KIF26B-20-GOOR | 20 (40 μL) | 200 μL |
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| TEF-KIF26B-20-GOGO | 20 (40 μL) | 200 μL |
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| TEF-KIF26B-20-GOGR | 20 (40 μL) | 200 μL |
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| TEF-KIF26B-20-GOAQ | 20 (40 μL) | 200 μL |
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| TEF-KIF26B-20-GRRE | 20 (40 μL) | 200 μL |
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| TEF-KIF26B-20-GROR | 20 (40 μL) | 200 μL |
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| TEF-KIF26B-20-GRGO | 20 (40 μL) | 200 μL |
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| TEF-KIF26B-20-GRGR | 20 (40 μL) | 200 μL |
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| TEF-KIF26B-20-GRAQ | 20 (40 μL) | 200 μL |
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| TEF-KIF26B-20-AQRE | 20 (40 μL) | 200 μL |
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| TEF-KIF26B-20-AQOR | 20 (40 μL) | 200 μL |
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| TEF-KIF26B-20-AQGO | 20 (40 μL) | 200 μL |
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| TEF-KIF26B-20-AQGR | 20 (40 μL) | 200 μL |
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| TEF-KIF26B-20-AQAQ | 20 (40 μL) | 200 μL |
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TEF Gene Summary
This gene encodes a member of the PAR (proline and acidic amino acid-rich) subfamily of basic region/leucine zipper (bZIP) transcription factors. It is expressed in a broad range of cells and tissues in adult animals, however, during embryonic development, TEF expression appears to be restricted to the developing anterior pituitary gland, coincident with the appearance of thyroid-stimulating hormone, beta (TSHB). Indeed, TEF can bind to, and transactivate the TSHB promoter. It shows homology (in the functional domains) with other members of the PAR-bZIP subfamily of transcription factors, which include albumin D box-binding protein (DBP), human hepatic leukemia factor (HLF) and chicken vitellogenin gene-binding protein (VBP); VBP is considered the chicken homologue of TEF. Different members of the subfamily can readily form heterodimers, and share DNA-binding, and transcriptional regulatory properties. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
Gene Name: TEF, PAR BZIP Transcription Factor
Chromosome: CHR22: 41763391 -41795330
Locus: 22q13.2
KIF26B Gene Summary
The protein encoded by this gene is an intracellular motor protein thought to transport organelles along microtubules. The encoded protein is required for kidney development. Elevated levels of this protein have been found in some breast and colorectal cancers. [provided by RefSeq, Mar 2017]
Gene Name: Kinesin Family Member 26B
Chromosome: CHR1: 245318286 -245866428
Locus: 1q44
Gene Diseases
The TEF KIF26B Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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