TECTA-FOXN3 Fusion FISH Probe
The TECTA-FOXN3 Fusion FISH Probe is used to confirm a fusion of the TECTA and FOXN3 genes. The fusion of the TECTA and FOXN3 genes has been associated with Pheochromocytoma And Paraganglioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TECTA-FOXN3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TECTA-FOXN3-20-RERE | 20 (40 μL) | 200 μL |
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| TECTA-FOXN3-20-REOR | 20 (40 μL) | 200 μL |
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| TECTA-FOXN3-20-REGO | 20 (40 μL) | 200 μL |
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| TECTA-FOXN3-20-REGR | 20 (40 μL) | 200 μL |
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| TECTA-FOXN3-20-REAQ | 20 (40 μL) | 200 μL |
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| TECTA-FOXN3-20-ORRE | 20 (40 μL) | 200 μL |
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| TECTA-FOXN3-20-OROR | 20 (40 μL) | 200 μL |
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| TECTA-FOXN3-20-ORGO | 20 (40 μL) | 200 μL |
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| TECTA-FOXN3-20-ORAQ | 20 (40 μL) | 200 μL |
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| TECTA-FOXN3-20-GORE | 20 (40 μL) | 200 μL |
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| TECTA-FOXN3-20-GOOR | 20 (40 μL) | 200 μL |
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| TECTA-FOXN3-20-GOGO | 20 (40 μL) | 200 μL |
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| TECTA-FOXN3-20-GOGR | 20 (40 μL) | 200 μL |
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| TECTA-FOXN3-20-GOAQ | 20 (40 μL) | 200 μL |
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| TECTA-FOXN3-20-GRRE | 20 (40 μL) | 200 μL |
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| TECTA-FOXN3-20-GROR | 20 (40 μL) | 200 μL |
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| TECTA-FOXN3-20-GRGO | 20 (40 μL) | 200 μL |
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| TECTA-FOXN3-20-GRGR | 20 (40 μL) | 200 μL |
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| TECTA-FOXN3-20-GRAQ | 20 (40 μL) | 200 μL |
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| TECTA-FOXN3-20-AQRE | 20 (40 μL) | 200 μL |
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| TECTA-FOXN3-20-AQOR | 20 (40 μL) | 200 μL |
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| TECTA-FOXN3-20-AQGO | 20 (40 μL) | 200 μL |
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| TECTA-FOXN3-20-AQGR | 20 (40 μL) | 200 μL |
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| TECTA-FOXN3-20-AQAQ | 20 (40 μL) | 200 μL |
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FOXN3 Gene Summary
This gene is a member of the forkhead/winged helix transcription factor family. Checkpoints are eukaryotic DNA damage-inducible cell cycle arrests at G1 and G2. Checkpoint suppressor 1 suppresses multiple yeast checkpoint mutations including mec1, rad9, rad53 and dun1 by activating a MEC1-independent checkpoint pathway. Alternative splicing is observed at the locus, resulting in distinct isoforms. [provided by RefSeq, Jul 2008]
Gene Name: Forkhead Box N3
Chromosome: CHR14: 89622515 -90085494
Locus: 14q31.3-q32.11
TECTA Gene Summary
The tectorial membrane is an extracellular matrix of the inner ear that contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia, and leads to fluctuations in hair-cell membrane potential, transducing sound into electrical signals. Alpha-tectorin is one of the major noncollagenous components of the tectorial membrane. Mutations in the TECTA gene have been shown to be responsible for autosomal dominant nonsyndromic hearing impairment and a recessive form of sensorineural pre-lingual non-syndromic deafness. [provided by RefSeq, Jul 2008]
Gene Name: Tectorin Alpha
Chromosome: CHR11: 120973374 -121061515
Locus: 11q23.3
Gene Diseases
The TECTA FOXN3 Fusion has been associated with the following diseases:
| Disease Name |
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| Pheochromocytoma And Paraganglioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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