TECR-ICAM3 Fusion FISH Probe
The TECR-ICAM3 Fusion FISH Probe is used to confirm a fusion of the TECR and ICAM3 genes. The fusion of the TECR and ICAM3 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TECR-ICAM3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TECR-ICAM3-20-RERE | 20 (40 μL) | 200 μL |
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| TECR-ICAM3-20-REOR | 20 (40 μL) | 200 μL |
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| TECR-ICAM3-20-REGO | 20 (40 μL) | 200 μL |
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| TECR-ICAM3-20-REGR | 20 (40 μL) | 200 μL |
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| TECR-ICAM3-20-REAQ | 20 (40 μL) | 200 μL |
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| TECR-ICAM3-20-ORRE | 20 (40 μL) | 200 μL |
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| TECR-ICAM3-20-OROR | 20 (40 μL) | 200 μL |
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| TECR-ICAM3-20-ORGO | 20 (40 μL) | 200 μL |
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| TECR-ICAM3-20-ORAQ | 20 (40 μL) | 200 μL |
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| TECR-ICAM3-20-GORE | 20 (40 μL) | 200 μL |
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| TECR-ICAM3-20-GOOR | 20 (40 μL) | 200 μL |
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| TECR-ICAM3-20-GOGO | 20 (40 μL) | 200 μL |
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| TECR-ICAM3-20-GOGR | 20 (40 μL) | 200 μL |
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| TECR-ICAM3-20-GOAQ | 20 (40 μL) | 200 μL |
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| TECR-ICAM3-20-GRRE | 20 (40 μL) | 200 μL |
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| TECR-ICAM3-20-GROR | 20 (40 μL) | 200 μL |
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| TECR-ICAM3-20-GRGO | 20 (40 μL) | 200 μL |
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| TECR-ICAM3-20-GRGR | 20 (40 μL) | 200 μL |
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| TECR-ICAM3-20-GRAQ | 20 (40 μL) | 200 μL |
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| TECR-ICAM3-20-AQRE | 20 (40 μL) | 200 μL |
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| TECR-ICAM3-20-AQOR | 20 (40 μL) | 200 μL |
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| TECR-ICAM3-20-AQGO | 20 (40 μL) | 200 μL |
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| TECR-ICAM3-20-AQGR | 20 (40 μL) | 200 μL |
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| TECR-ICAM3-20-AQAQ | 20 (40 μL) | 200 μL |
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ICAM3 Gene Summary
The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016]
Gene Name: Intercellular Adhesion Molecule 3
Chromosome: CHR19: 10444451 -10450345
Locus: 19p13.2
TECR Gene Summary
This gene encodes a multi-pass membrane protein that resides in the endoplasmic reticulum, and belongs to the steroid 5-alpha reductase family. The elongation of microsomal long and very long chain fatty acid consists of 4 sequential reactions. This protein catalyzes the final step, reducing trans-2,3-enoyl-CoA to saturated acyl-CoA. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Apr 2011]
Gene Name: Trans-2,3-enoyl-CoA Reductase
Chromosome: CHR19: 14640378 -14676792
Locus: 19p13.12
Gene Diseases
The TECR ICAM3 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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