TEC-PASD1 Fusion FISH Probe
The TEC-PASD1 Fusion FISH Probe is used to confirm a fusion of the TEC and PASD1 genes. The fusion of the TEC and PASD1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TEC-PASD1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TEC-PASD1-20-RERE | 20 (40 μL) | 200 μL |
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| TEC-PASD1-20-REOR | 20 (40 μL) | 200 μL |
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| TEC-PASD1-20-REGO | 20 (40 μL) | 200 μL |
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| TEC-PASD1-20-REGR | 20 (40 μL) | 200 μL |
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| TEC-PASD1-20-REAQ | 20 (40 μL) | 200 μL |
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| TEC-PASD1-20-ORRE | 20 (40 μL) | 200 μL |
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| TEC-PASD1-20-OROR | 20 (40 μL) | 200 μL |
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| TEC-PASD1-20-ORGO | 20 (40 μL) | 200 μL |
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| TEC-PASD1-20-ORAQ | 20 (40 μL) | 200 μL |
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| TEC-PASD1-20-GORE | 20 (40 μL) | 200 μL |
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| TEC-PASD1-20-GOOR | 20 (40 μL) | 200 μL |
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| TEC-PASD1-20-GOGO | 20 (40 μL) | 200 μL |
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| TEC-PASD1-20-GOGR | 20 (40 μL) | 200 μL |
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| TEC-PASD1-20-GOAQ | 20 (40 μL) | 200 μL |
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| TEC-PASD1-20-GRRE | 20 (40 μL) | 200 μL |
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| TEC-PASD1-20-GROR | 20 (40 μL) | 200 μL |
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| TEC-PASD1-20-GRGO | 20 (40 μL) | 200 μL |
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| TEC-PASD1-20-GRGR | 20 (40 μL) | 200 μL |
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| TEC-PASD1-20-GRAQ | 20 (40 μL) | 200 μL |
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| TEC-PASD1-20-AQRE | 20 (40 μL) | 200 μL |
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| TEC-PASD1-20-AQOR | 20 (40 μL) | 200 μL |
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| TEC-PASD1-20-AQGO | 20 (40 μL) | 200 μL |
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| TEC-PASD1-20-AQGR | 20 (40 μL) | 200 μL |
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| TEC-PASD1-20-AQAQ | 20 (40 μL) | 200 μL |
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TEC Gene Summary
The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome. [provided by RefSeq, Jul 2008]
Gene Name: Tec Protein Tyrosine Kinase
Chromosome: CHR4: 48137799 -48271814
Locus: 4p12-p11
PASD1 Gene Summary
This gene encodes a protein that is thought to function as a transcription factor. The protein is a cancer-associated antigen that can stimulate autologous T-cell responses, and it is therefore considered to be a potential immunotherapeutic target for the treatment of various hematopoietic malignancies, including diffuse large B-cell lymphoma. [provided by RefSeq, May 2010]
Gene Name: PAS Domain Containing Repressor 1
Chromosome: CHRX: 150732006 -150845211
Locus: Xq28
Gene Diseases
The TEC PASD1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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