TEAD4-TULP3 Fusion FISH Probe
The TEAD4-TULP3 Fusion FISH Probe is used to confirm a fusion of the TEAD4 and TULP3 genes. The fusion of the TEAD4 and TULP3 genes has been associated with Kidney Renal Clear Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TEAD4-TULP3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TEAD4-TULP3-20-RERE | 20 (40 μL) | 200 μL |
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| TEAD4-TULP3-20-REOR | 20 (40 μL) | 200 μL |
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| TEAD4-TULP3-20-REGO | 20 (40 μL) | 200 μL |
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| TEAD4-TULP3-20-REGR | 20 (40 μL) | 200 μL |
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| TEAD4-TULP3-20-REAQ | 20 (40 μL) | 200 μL |
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| TEAD4-TULP3-20-ORRE | 20 (40 μL) | 200 μL |
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| TEAD4-TULP3-20-OROR | 20 (40 μL) | 200 μL |
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| TEAD4-TULP3-20-ORGO | 20 (40 μL) | 200 μL |
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| TEAD4-TULP3-20-ORAQ | 20 (40 μL) | 200 μL |
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| TEAD4-TULP3-20-GORE | 20 (40 μL) | 200 μL |
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| TEAD4-TULP3-20-GOOR | 20 (40 μL) | 200 μL |
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| TEAD4-TULP3-20-GOGO | 20 (40 μL) | 200 μL |
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| TEAD4-TULP3-20-GOGR | 20 (40 μL) | 200 μL |
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| TEAD4-TULP3-20-GOAQ | 20 (40 μL) | 200 μL |
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| TEAD4-TULP3-20-GRRE | 20 (40 μL) | 200 μL |
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| TEAD4-TULP3-20-GROR | 20 (40 μL) | 200 μL |
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| TEAD4-TULP3-20-GRGO | 20 (40 μL) | 200 μL |
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| TEAD4-TULP3-20-GRGR | 20 (40 μL) | 200 μL |
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| TEAD4-TULP3-20-GRAQ | 20 (40 μL) | 200 μL |
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| TEAD4-TULP3-20-AQRE | 20 (40 μL) | 200 μL |
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| TEAD4-TULP3-20-AQOR | 20 (40 μL) | 200 μL |
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| TEAD4-TULP3-20-AQGO | 20 (40 μL) | 200 μL |
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| TEAD4-TULP3-20-AQGR | 20 (40 μL) | 200 μL |
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| TEAD4-TULP3-20-AQAQ | 20 (40 μL) | 200 μL |
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TEAD4 Gene Summary
This gene product is a member of the transcriptional enhancer factor (TEF) family of transcription factors, which contain the TEA/ATTS DNA-binding domain. It is preferentially expressed in the skeletal muscle, and binds to the M-CAT regulatory element found in promoters of muscle-specific genes to direct their gene expression. Alternatively spliced transcripts encoding distinct isoforms, some of which are translated through the use of a non-AUG (UUG) initiation codon, have been described for this gene. [provided by RefSeq, Jul 2008]
Gene Name: TEA Domain Transcription Factor 4
Chromosome: CHR12: 3068477 -3149842
Locus: 12p13.33
TULP3 Gene Summary
This gene encodes a member of the tubby gene family of bipartite transcription factors. Members of this family have been identified in plants, vertebrates, and invertebrates, and they share a conserved N-terminal transcription activation region and a conserved C-terminal DNA and phosphatidylinositol-phosphate binding region. The encoded protein binds to phosphoinositides in the plasma membrane via its C-terminal region and probably functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis, for instance, induced by G-protein-coupled-receptor signaling. It plays an important role in neuronal development and function. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, May 2009]
Gene Name: Tubby Like Protein 3
Chromosome: CHR12: 3000032 -3050306
Locus: 12p13.33
Gene Diseases
The TEAD4 TULP3 Fusion has been associated with the following diseases:
| Disease Name |
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| Kidney Renal Clear Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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