TEAD4-ERC1 Fusion FISH Probe
The TEAD4-ERC1 Fusion FISH Probe is used to confirm a fusion of the TEAD4 and ERC1 genes. The fusion of the TEAD4 and ERC1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TEAD4-ERC1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TEAD4-ERC1-20-RERE | 20 (40 μL) | 200 μL |
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| TEAD4-ERC1-20-REOR | 20 (40 μL) | 200 μL |
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| TEAD4-ERC1-20-REGO | 20 (40 μL) | 200 μL |
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| TEAD4-ERC1-20-REGR | 20 (40 μL) | 200 μL |
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| TEAD4-ERC1-20-REAQ | 20 (40 μL) | 200 μL |
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| TEAD4-ERC1-20-ORRE | 20 (40 μL) | 200 μL |
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| TEAD4-ERC1-20-OROR | 20 (40 μL) | 200 μL |
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| TEAD4-ERC1-20-ORGO | 20 (40 μL) | 200 μL |
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| TEAD4-ERC1-20-ORAQ | 20 (40 μL) | 200 μL |
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| TEAD4-ERC1-20-GORE | 20 (40 μL) | 200 μL |
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| TEAD4-ERC1-20-GOOR | 20 (40 μL) | 200 μL |
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| TEAD4-ERC1-20-GOGO | 20 (40 μL) | 200 μL |
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| TEAD4-ERC1-20-GOGR | 20 (40 μL) | 200 μL |
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| TEAD4-ERC1-20-GOAQ | 20 (40 μL) | 200 μL |
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| TEAD4-ERC1-20-GRRE | 20 (40 μL) | 200 μL |
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| TEAD4-ERC1-20-GROR | 20 (40 μL) | 200 μL |
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| TEAD4-ERC1-20-GRGO | 20 (40 μL) | 200 μL |
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| TEAD4-ERC1-20-GRGR | 20 (40 μL) | 200 μL |
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| TEAD4-ERC1-20-GRAQ | 20 (40 μL) | 200 μL |
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| TEAD4-ERC1-20-AQRE | 20 (40 μL) | 200 μL |
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| TEAD4-ERC1-20-AQOR | 20 (40 μL) | 200 μL |
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| TEAD4-ERC1-20-AQGO | 20 (40 μL) | 200 μL |
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| TEAD4-ERC1-20-AQGR | 20 (40 μL) | 200 μL |
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| TEAD4-ERC1-20-AQAQ | 20 (40 μL) | 200 μL |
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TEAD4 Gene Summary
This gene product is a member of the transcriptional enhancer factor (TEF) family of transcription factors, which contain the TEA/ATTS DNA-binding domain. It is preferentially expressed in the skeletal muscle, and binds to the M-CAT regulatory element found in promoters of muscle-specific genes to direct their gene expression. Alternatively spliced transcripts encoding distinct isoforms, some of which are translated through the use of a non-AUG (UUG) initiation codon, have been described for this gene. [provided by RefSeq, Jul 2008]
Gene Name: TEA Domain Transcription Factor 4
Chromosome: CHR12: 3068477 -3149842
Locus: 12p13.33
ERC1 Gene Summary
The protein encoded by this gene is a member of a family of RIM-binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor-type tyrosine kinase gene RET by gene rearrangement due to the translocation t(10;12)(q11;p13) in thyroid papillary carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Gene Name: ELKS/RAB6-interacting/CAST Family Member 1
Chromosome: CHR12: 1100403 -1605099
Locus: 12p13.33
Gene Diseases
The TEAD4 ERC1 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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