SEARCH OUR PRODUCT CATALOG

TEAD1-ZCCHC8 Fusion FISH Probe

The TEAD1-ZCCHC8 Fusion FISH Probe is used to confirm a fusion of the TEAD1 and ZCCHC8 genes. The fusion of the TEAD1 and ZCCHC8 genes has been associated with Liver Hepatocellular Carcinoma, and Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
TEAD1-ZCCHC8-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
TEAD1-ZCCHC8-20-RERE 20 (40 μL) 200 μL
TEAD1-ZCCHC8-20-REOR 20 (40 μL) 200 μL
TEAD1-ZCCHC8-20-REGO 20 (40 μL) 200 μL
TEAD1-ZCCHC8-20-REGR 20 (40 μL) 200 μL
TEAD1-ZCCHC8-20-REAQ 20 (40 μL) 200 μL
TEAD1-ZCCHC8-20-ORRE 20 (40 μL) 200 μL
TEAD1-ZCCHC8-20-OROR 20 (40 μL) 200 μL
TEAD1-ZCCHC8-20-ORGO 20 (40 μL) 200 μL
TEAD1-ZCCHC8-20-ORAQ 20 (40 μL) 200 μL
TEAD1-ZCCHC8-20-GORE 20 (40 μL) 200 μL
TEAD1-ZCCHC8-20-GOOR 20 (40 μL) 200 μL
TEAD1-ZCCHC8-20-GOGO 20 (40 μL) 200 μL
TEAD1-ZCCHC8-20-GOGR 20 (40 μL) 200 μL
TEAD1-ZCCHC8-20-GOAQ 20 (40 μL) 200 μL
TEAD1-ZCCHC8-20-GRRE 20 (40 μL) 200 μL
TEAD1-ZCCHC8-20-GROR 20 (40 μL) 200 μL
TEAD1-ZCCHC8-20-GRGO 20 (40 μL) 200 μL
TEAD1-ZCCHC8-20-GRGR 20 (40 μL) 200 μL
TEAD1-ZCCHC8-20-GRAQ 20 (40 μL) 200 μL
TEAD1-ZCCHC8-20-AQRE 20 (40 μL) 200 μL
TEAD1-ZCCHC8-20-AQOR 20 (40 μL) 200 μL
TEAD1-ZCCHC8-20-AQGO 20 (40 μL) 200 μL
TEAD1-ZCCHC8-20-AQGR 20 (40 μL) 200 μL
TEAD1-ZCCHC8-20-AQAQ 20 (40 μL) 200 μL

TEAD1 Gene Summary

This gene encodes a ubiquitous transcriptional enhancer factor that is a member of the TEA/ATTS domain family. This protein directs the transactivation of a wide variety of genes and, in placental cells, also acts as a transcriptional repressor. Mutations in this gene cause Sveinsson's chorioretinal atrophy. Additional transcript variants have been described but their full-length natures have not been experimentally verified. [provided by RefSeq, May 2010]

Gene Name: TEA Domain Transcription Factor 1

Chromosome: CHR11: 12695968 -12966284

Locus: 11p15.3

ZCCHC8 Gene Summary

This gene encodes a scaffold protein which serves as an assessory factor to the nuclear RNA exosome complex. The encoded protein forms a trimeric human nuclear exosome targeting (NEXT) complex, together with hMTR4 and the RNA-binding factor RBM7 which promotes the exosomal degradation of non-coding promoter-upstream transcripts, enhancer RNAs and 3'-extended products of histone- and small nuclear RNA transcription. This complex is also thought to recruit the exosome to degrade intronic RNAs via its interaction with both the exosome and the spliceosome. It contains both an N-terminal zinc-knuckle domain and a C-terminal proline-rich domain. [provided by RefSeq, Apr 2017]

Gene Name: Zinc Finger CCHC-type Containing 8

Chromosome: CHR12: 122956145 -122985543

Locus: 12q24.31

Gene Diseases

The TEAD1 ZCCHC8 Fusion has been associated with the following diseases:

Disease Name
Liver Hepatocellular Carcinoma
Liver Hepatocellular Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.