TEAD1-ZCCHC8 Fusion FISH Probe
The TEAD1-ZCCHC8 Fusion FISH Probe is used to confirm a fusion of the TEAD1 and ZCCHC8 genes. The fusion of the TEAD1 and ZCCHC8 genes has been associated with Liver Hepatocellular Carcinoma, and Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TEAD1-ZCCHC8-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TEAD1-ZCCHC8-20-RERE | 20 (40 μL) | 200 μL |
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| TEAD1-ZCCHC8-20-REOR | 20 (40 μL) | 200 μL |
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| TEAD1-ZCCHC8-20-REGO | 20 (40 μL) | 200 μL |
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| TEAD1-ZCCHC8-20-REGR | 20 (40 μL) | 200 μL |
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| TEAD1-ZCCHC8-20-REAQ | 20 (40 μL) | 200 μL |
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| TEAD1-ZCCHC8-20-ORRE | 20 (40 μL) | 200 μL |
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| TEAD1-ZCCHC8-20-OROR | 20 (40 μL) | 200 μL |
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| TEAD1-ZCCHC8-20-ORGO | 20 (40 μL) | 200 μL |
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| TEAD1-ZCCHC8-20-ORAQ | 20 (40 μL) | 200 μL |
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| TEAD1-ZCCHC8-20-GORE | 20 (40 μL) | 200 μL |
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| TEAD1-ZCCHC8-20-GOOR | 20 (40 μL) | 200 μL |
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| TEAD1-ZCCHC8-20-GOGO | 20 (40 μL) | 200 μL |
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| TEAD1-ZCCHC8-20-GOGR | 20 (40 μL) | 200 μL |
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| TEAD1-ZCCHC8-20-GOAQ | 20 (40 μL) | 200 μL |
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| TEAD1-ZCCHC8-20-GRRE | 20 (40 μL) | 200 μL |
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| TEAD1-ZCCHC8-20-GROR | 20 (40 μL) | 200 μL |
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| TEAD1-ZCCHC8-20-GRGO | 20 (40 μL) | 200 μL |
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| TEAD1-ZCCHC8-20-GRGR | 20 (40 μL) | 200 μL |
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| TEAD1-ZCCHC8-20-GRAQ | 20 (40 μL) | 200 μL |
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| TEAD1-ZCCHC8-20-AQRE | 20 (40 μL) | 200 μL |
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| TEAD1-ZCCHC8-20-AQOR | 20 (40 μL) | 200 μL |
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| TEAD1-ZCCHC8-20-AQGO | 20 (40 μL) | 200 μL |
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| TEAD1-ZCCHC8-20-AQGR | 20 (40 μL) | 200 μL |
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| TEAD1-ZCCHC8-20-AQAQ | 20 (40 μL) | 200 μL |
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TEAD1 Gene Summary
This gene encodes a ubiquitous transcriptional enhancer factor that is a member of the TEA/ATTS domain family. This protein directs the transactivation of a wide variety of genes and, in placental cells, also acts as a transcriptional repressor. Mutations in this gene cause Sveinsson's chorioretinal atrophy. Additional transcript variants have been described but their full-length natures have not been experimentally verified. [provided by RefSeq, May 2010]
Gene Name: TEA Domain Transcription Factor 1
Chromosome: CHR11: 12695968 -12966284
Locus: 11p15.3
ZCCHC8 Gene Summary
This gene encodes a scaffold protein which serves as an assessory factor to the nuclear RNA exosome complex. The encoded protein forms a trimeric human nuclear exosome targeting (NEXT) complex, together with hMTR4 and the RNA-binding factor RBM7 which promotes the exosomal degradation of non-coding promoter-upstream transcripts, enhancer RNAs and 3'-extended products of histone- and small nuclear RNA transcription. This complex is also thought to recruit the exosome to degrade intronic RNAs via its interaction with both the exosome and the spliceosome. It contains both an N-terminal zinc-knuckle domain and a C-terminal proline-rich domain. [provided by RefSeq, Apr 2017]
Gene Name: Zinc Finger CCHC-type Containing 8
Chromosome: CHR12: 122956145 -122985543
Locus: 12q24.31
Gene Diseases
The TEAD1 ZCCHC8 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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