TEAD1-UVRAG Fusion FISH Probe
The TEAD1-UVRAG Fusion FISH Probe is used to confirm a fusion of the TEAD1 and UVRAG genes. The fusion of the TEAD1 and UVRAG genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TEAD1-UVRAG-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| TEAD1-UVRAG-20-RERE | 20 (40 μL) | 200 μL |
|
|
| TEAD1-UVRAG-20-REOR | 20 (40 μL) | 200 μL |
|
|
| TEAD1-UVRAG-20-REGO | 20 (40 μL) | 200 μL |
|
|
| TEAD1-UVRAG-20-REGR | 20 (40 μL) | 200 μL |
|
|
| TEAD1-UVRAG-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| TEAD1-UVRAG-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| TEAD1-UVRAG-20-OROR | 20 (40 μL) | 200 μL |
|
|
| TEAD1-UVRAG-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| TEAD1-UVRAG-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| TEAD1-UVRAG-20-GORE | 20 (40 μL) | 200 μL |
|
|
| TEAD1-UVRAG-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| TEAD1-UVRAG-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| TEAD1-UVRAG-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| TEAD1-UVRAG-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| TEAD1-UVRAG-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| TEAD1-UVRAG-20-GROR | 20 (40 μL) | 200 μL |
|
|
| TEAD1-UVRAG-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| TEAD1-UVRAG-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| TEAD1-UVRAG-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| TEAD1-UVRAG-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| TEAD1-UVRAG-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| TEAD1-UVRAG-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| TEAD1-UVRAG-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| TEAD1-UVRAG-20-AQAQ | 20 (40 μL) | 200 μL |
|
TEAD1 Gene Summary
This gene encodes a ubiquitous transcriptional enhancer factor that is a member of the TEA/ATTS domain family. This protein directs the transactivation of a wide variety of genes and, in placental cells, also acts as a transcriptional repressor. Mutations in this gene cause Sveinsson's chorioretinal atrophy. Additional transcript variants have been described but their full-length natures have not been experimentally verified. [provided by RefSeq, May 2010]
Gene Name: TEA Domain Transcription Factor 1
Chromosome: CHR11: 12695968 -12966284
Locus: 11p15.3
UVRAG Gene Summary
This gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer. [provided by RefSeq, Jul 2008]
Gene Name: UV Radiation Resistance Associated
Chromosome: CHR11: 75526211 -75855282
Locus: 11q13.5
Gene Diseases
The TEAD1 UVRAG Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|