TEAD1-PARVA Fusion FISH Probe
The TEAD1-PARVA Fusion FISH Probe is used to confirm a fusion of the TEAD1 and PARVA genes. The fusion of the TEAD1 and PARVA genes has been associated with Breast Invasive Carcinoma, Breast Invasive Carcinoma, and Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TEAD1-PARVA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TEAD1-PARVA-20-RERE | 20 (40 μL) | 200 μL |
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| TEAD1-PARVA-20-REOR | 20 (40 μL) | 200 μL |
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| TEAD1-PARVA-20-REGO | 20 (40 μL) | 200 μL |
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| TEAD1-PARVA-20-REGR | 20 (40 μL) | 200 μL |
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| TEAD1-PARVA-20-REAQ | 20 (40 μL) | 200 μL |
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| TEAD1-PARVA-20-ORRE | 20 (40 μL) | 200 μL |
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| TEAD1-PARVA-20-OROR | 20 (40 μL) | 200 μL |
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| TEAD1-PARVA-20-ORGO | 20 (40 μL) | 200 μL |
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| TEAD1-PARVA-20-ORAQ | 20 (40 μL) | 200 μL |
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| TEAD1-PARVA-20-GORE | 20 (40 μL) | 200 μL |
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| TEAD1-PARVA-20-GOOR | 20 (40 μL) | 200 μL |
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| TEAD1-PARVA-20-GOGO | 20 (40 μL) | 200 μL |
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| TEAD1-PARVA-20-GOGR | 20 (40 μL) | 200 μL |
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| TEAD1-PARVA-20-GOAQ | 20 (40 μL) | 200 μL |
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| TEAD1-PARVA-20-GRRE | 20 (40 μL) | 200 μL |
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| TEAD1-PARVA-20-GROR | 20 (40 μL) | 200 μL |
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| TEAD1-PARVA-20-GRGO | 20 (40 μL) | 200 μL |
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| TEAD1-PARVA-20-GRGR | 20 (40 μL) | 200 μL |
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| TEAD1-PARVA-20-GRAQ | 20 (40 μL) | 200 μL |
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| TEAD1-PARVA-20-AQRE | 20 (40 μL) | 200 μL |
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| TEAD1-PARVA-20-AQOR | 20 (40 μL) | 200 μL |
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| TEAD1-PARVA-20-AQGO | 20 (40 μL) | 200 μL |
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| TEAD1-PARVA-20-AQGR | 20 (40 μL) | 200 μL |
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| TEAD1-PARVA-20-AQAQ | 20 (40 μL) | 200 μL |
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TEAD1 Gene Summary
This gene encodes a ubiquitous transcriptional enhancer factor that is a member of the TEA/ATTS domain family. This protein directs the transactivation of a wide variety of genes and, in placental cells, also acts as a transcriptional repressor. Mutations in this gene cause Sveinsson's chorioretinal atrophy. Additional transcript variants have been described but their full-length natures have not been experimentally verified. [provided by RefSeq, May 2010]
Gene Name: TEA Domain Transcription Factor 1
Chromosome: CHR11: 12695968 -12966284
Locus: 11p15.3
PARVA Gene Summary
This gene encodes a member of the parvin family of actin-binding proteins. Parvins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. The encoded protein is part of the integrin-linked kinase signaling complex and plays a role in cell adhesion, motility and survival. [provided by RefSeq, Dec 2010]
Gene Name: Parvin Alpha
Chromosome: CHR11: 12399025 -12556903
Locus: 11p15.3
Gene Diseases
The TEAD1 PARVA Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
| Breast Invasive Carcinoma |
| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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