TEAD1-FAR1 Fusion FISH Probe
The TEAD1-FAR1 Fusion FISH Probe is used to confirm a fusion of the TEAD1 and FAR1 genes. The fusion of the TEAD1 and FAR1 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TEAD1-FAR1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TEAD1-FAR1-20-RERE | 20 (40 μL) | 200 μL |
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| TEAD1-FAR1-20-REOR | 20 (40 μL) | 200 μL |
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| TEAD1-FAR1-20-REGO | 20 (40 μL) | 200 μL |
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| TEAD1-FAR1-20-REGR | 20 (40 μL) | 200 μL |
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| TEAD1-FAR1-20-REAQ | 20 (40 μL) | 200 μL |
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| TEAD1-FAR1-20-ORRE | 20 (40 μL) | 200 μL |
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| TEAD1-FAR1-20-OROR | 20 (40 μL) | 200 μL |
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| TEAD1-FAR1-20-ORGO | 20 (40 μL) | 200 μL |
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| TEAD1-FAR1-20-ORAQ | 20 (40 μL) | 200 μL |
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| TEAD1-FAR1-20-GORE | 20 (40 μL) | 200 μL |
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| TEAD1-FAR1-20-GOOR | 20 (40 μL) | 200 μL |
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| TEAD1-FAR1-20-GOGO | 20 (40 μL) | 200 μL |
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| TEAD1-FAR1-20-GOGR | 20 (40 μL) | 200 μL |
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| TEAD1-FAR1-20-GOAQ | 20 (40 μL) | 200 μL |
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| TEAD1-FAR1-20-GRRE | 20 (40 μL) | 200 μL |
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| TEAD1-FAR1-20-GROR | 20 (40 μL) | 200 μL |
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| TEAD1-FAR1-20-GRGO | 20 (40 μL) | 200 μL |
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| TEAD1-FAR1-20-GRGR | 20 (40 μL) | 200 μL |
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| TEAD1-FAR1-20-GRAQ | 20 (40 μL) | 200 μL |
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| TEAD1-FAR1-20-AQRE | 20 (40 μL) | 200 μL |
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| TEAD1-FAR1-20-AQOR | 20 (40 μL) | 200 μL |
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| TEAD1-FAR1-20-AQGO | 20 (40 μL) | 200 μL |
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| TEAD1-FAR1-20-AQGR | 20 (40 μL) | 200 μL |
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| TEAD1-FAR1-20-AQAQ | 20 (40 μL) | 200 μL |
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TEAD1 Gene Summary
This gene encodes a ubiquitous transcriptional enhancer factor that is a member of the TEA/ATTS domain family. This protein directs the transactivation of a wide variety of genes and, in placental cells, also acts as a transcriptional repressor. Mutations in this gene cause Sveinsson's chorioretinal atrophy. Additional transcript variants have been described but their full-length natures have not been experimentally verified. [provided by RefSeq, May 2010]
Gene Name: TEA Domain Transcription Factor 1
Chromosome: CHR11: 12695968 -12966284
Locus: 11p15.3
FAR1 Gene Summary
The protein encoded by this gene is required for the reduction of fatty acids to fatty alcohols, a process that is required for the synthesis of monoesters and ether lipids. NADPH is required as a cofactor in this reaction, and 16-18 carbon saturated and unsaturated fatty acids are the preferred substrate. This is a peroxisomal membrane protein, and studies suggest that the N-terminus contains a large catalytic domain located on the outside of the peroxisome, while the C-terminus is exposed to the matrix of the peroxisome. Studies indicate that the regulation of this protein is dependent on plasmalogen levels. Mutations in this gene have been associated with individuals affected by severe intellectual disability, early-onset epilepsy, microcephaly, congenital cataracts, growth retardation, and spasticity (PMID: 25439727). A pseudogene of this gene is located on chromosome 13. [provided by RefSeq, Jan 2015]
Gene Name: Fatty Acyl-CoA Reductase 1
Chromosome: CHR11: 13690205 -13753893
Locus: 11p15.3
Gene Diseases
The TEAD1 FAR1 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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