TCTN3-DHCR24 Fusion FISH Probe
The TCTN3-DHCR24 Fusion FISH Probe is used to confirm a fusion of the TCTN3 and DHCR24 genes. The fusion of the TCTN3 and DHCR24 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TCTN3-DHCR24-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TCTN3-DHCR24-20-RERE | 20 (40 μL) | 200 μL |
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| TCTN3-DHCR24-20-REOR | 20 (40 μL) | 200 μL |
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| TCTN3-DHCR24-20-REGO | 20 (40 μL) | 200 μL |
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| TCTN3-DHCR24-20-REGR | 20 (40 μL) | 200 μL |
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| TCTN3-DHCR24-20-REAQ | 20 (40 μL) | 200 μL |
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| TCTN3-DHCR24-20-ORRE | 20 (40 μL) | 200 μL |
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| TCTN3-DHCR24-20-OROR | 20 (40 μL) | 200 μL |
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| TCTN3-DHCR24-20-ORGO | 20 (40 μL) | 200 μL |
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| TCTN3-DHCR24-20-ORAQ | 20 (40 μL) | 200 μL |
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| TCTN3-DHCR24-20-GORE | 20 (40 μL) | 200 μL |
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| TCTN3-DHCR24-20-GOOR | 20 (40 μL) | 200 μL |
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| TCTN3-DHCR24-20-GOGO | 20 (40 μL) | 200 μL |
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| TCTN3-DHCR24-20-GOGR | 20 (40 μL) | 200 μL |
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| TCTN3-DHCR24-20-GOAQ | 20 (40 μL) | 200 μL |
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| TCTN3-DHCR24-20-GRRE | 20 (40 μL) | 200 μL |
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| TCTN3-DHCR24-20-GROR | 20 (40 μL) | 200 μL |
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| TCTN3-DHCR24-20-GRGO | 20 (40 μL) | 200 μL |
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| TCTN3-DHCR24-20-GRGR | 20 (40 μL) | 200 μL |
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| TCTN3-DHCR24-20-GRAQ | 20 (40 μL) | 200 μL |
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| TCTN3-DHCR24-20-AQRE | 20 (40 μL) | 200 μL |
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| TCTN3-DHCR24-20-AQOR | 20 (40 μL) | 200 μL |
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| TCTN3-DHCR24-20-AQGO | 20 (40 μL) | 200 μL |
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| TCTN3-DHCR24-20-AQGR | 20 (40 μL) | 200 μL |
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| TCTN3-DHCR24-20-AQAQ | 20 (40 μL) | 200 μL |
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DHCR24 Gene Summary
This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells. [provided by RefSeq, Jul 2008]
Gene Name: 24-dehydrocholesterol Reductase
Chromosome: CHR1: 55315299 -55352921
Locus: 1p32.3
TCTN3 Gene Summary
This gene encodes a member of the tectonic gene family which functions in Hedgehog signal transduction and development of the neural tube. Mutations in this gene have been associated with Orofaciodigital Syndrome IV and Joubert Syndrom 18. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2012]
Gene Name: Tectonic Family Member 3
Chromosome: CHR10: 97423152 -97453900
Locus: 10q24.1
Gene Diseases
The TCTN3 DHCR24 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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