TCIRG1-TMC5 Fusion FISH Probe
The TCIRG1-TMC5 Fusion FISH Probe is used to confirm a fusion of the TCIRG1 and TMC5 genes. The fusion of the TCIRG1 and TMC5 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TCIRG1-TMC5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TCIRG1-TMC5-20-RERE | 20 (40 μL) | 200 μL |
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| TCIRG1-TMC5-20-REOR | 20 (40 μL) | 200 μL |
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| TCIRG1-TMC5-20-REGO | 20 (40 μL) | 200 μL |
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| TCIRG1-TMC5-20-REGR | 20 (40 μL) | 200 μL |
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| TCIRG1-TMC5-20-REAQ | 20 (40 μL) | 200 μL |
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| TCIRG1-TMC5-20-ORRE | 20 (40 μL) | 200 μL |
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| TCIRG1-TMC5-20-OROR | 20 (40 μL) | 200 μL |
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| TCIRG1-TMC5-20-ORGO | 20 (40 μL) | 200 μL |
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| TCIRG1-TMC5-20-ORAQ | 20 (40 μL) | 200 μL |
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| TCIRG1-TMC5-20-GORE | 20 (40 μL) | 200 μL |
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| TCIRG1-TMC5-20-GOOR | 20 (40 μL) | 200 μL |
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| TCIRG1-TMC5-20-GOGO | 20 (40 μL) | 200 μL |
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| TCIRG1-TMC5-20-GOGR | 20 (40 μL) | 200 μL |
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| TCIRG1-TMC5-20-GOAQ | 20 (40 μL) | 200 μL |
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| TCIRG1-TMC5-20-GRRE | 20 (40 μL) | 200 μL |
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| TCIRG1-TMC5-20-GROR | 20 (40 μL) | 200 μL |
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| TCIRG1-TMC5-20-GRGO | 20 (40 μL) | 200 μL |
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| TCIRG1-TMC5-20-GRGR | 20 (40 μL) | 200 μL |
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| TCIRG1-TMC5-20-GRAQ | 20 (40 μL) | 200 μL |
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| TCIRG1-TMC5-20-AQRE | 20 (40 μL) | 200 μL |
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| TCIRG1-TMC5-20-AQOR | 20 (40 μL) | 200 μL |
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| TCIRG1-TMC5-20-AQGO | 20 (40 μL) | 200 μL |
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| TCIRG1-TMC5-20-AQGR | 20 (40 μL) | 200 μL |
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| TCIRG1-TMC5-20-AQAQ | 20 (40 μL) | 200 μL |
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TCIRG1 Gene Summary
This gene encodes a subunit of a large protein complex known as a vacuolar H+-ATPase (V-ATPase). The protein complex acts as a pump to move protons across the membrane. This movement of protons helps regulate the pH of cells and their surrounding environment. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. V-ATPase is comprised of a cytosolic V1 domain and a transmembrane V0 domain. Alternative splicing results in multiple transcript variants. Mutations in this gene are associated with infantile malignant osteopetrosis. [provided by RefSeq, May 2017]
Gene Name: T-cell Immune Regulator 1, ATPase H+ Transporting V0 Subunit A3
Chromosome: CHR11: 67806461 -67818366
Locus: 11q13.2
TMC5 Gene Summary
The Transmembrane Channel Like 5 (TMC5) gene is located on chr16 :19422056-19510434 at 16p12.3.
Gene Name: Transmembrane Channel Like 5
Chromosome: CHR16: 19422056 -19510434
Locus: 16p12.3
Gene Diseases
The TCIRG1 TMC5 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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