TCF7L2-TACC2 Fusion FISH Probe
The TCF7L2-TACC2 Fusion FISH Probe is used to confirm a fusion of the TCF7L2 and TACC2 genes. The fusion of the TCF7L2 and TACC2 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TCF7L2-TACC2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TCF7L2-TACC2-20-RERE | 20 (40 μL) | 200 μL |
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| TCF7L2-TACC2-20-REOR | 20 (40 μL) | 200 μL |
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| TCF7L2-TACC2-20-REGO | 20 (40 μL) | 200 μL |
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| TCF7L2-TACC2-20-REGR | 20 (40 μL) | 200 μL |
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| TCF7L2-TACC2-20-REAQ | 20 (40 μL) | 200 μL |
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| TCF7L2-TACC2-20-ORRE | 20 (40 μL) | 200 μL |
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| TCF7L2-TACC2-20-OROR | 20 (40 μL) | 200 μL |
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| TCF7L2-TACC2-20-ORGO | 20 (40 μL) | 200 μL |
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| TCF7L2-TACC2-20-ORAQ | 20 (40 μL) | 200 μL |
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| TCF7L2-TACC2-20-GORE | 20 (40 μL) | 200 μL |
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| TCF7L2-TACC2-20-GOOR | 20 (40 μL) | 200 μL |
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| TCF7L2-TACC2-20-GOGO | 20 (40 μL) | 200 μL |
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| TCF7L2-TACC2-20-GOGR | 20 (40 μL) | 200 μL |
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| TCF7L2-TACC2-20-GOAQ | 20 (40 μL) | 200 μL |
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| TCF7L2-TACC2-20-GRRE | 20 (40 μL) | 200 μL |
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| TCF7L2-TACC2-20-GROR | 20 (40 μL) | 200 μL |
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| TCF7L2-TACC2-20-GRGO | 20 (40 μL) | 200 μL |
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| TCF7L2-TACC2-20-GRGR | 20 (40 μL) | 200 μL |
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| TCF7L2-TACC2-20-GRAQ | 20 (40 μL) | 200 μL |
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| TCF7L2-TACC2-20-AQRE | 20 (40 μL) | 200 μL |
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| TCF7L2-TACC2-20-AQOR | 20 (40 μL) | 200 μL |
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| TCF7L2-TACC2-20-AQGO | 20 (40 μL) | 200 μL |
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| TCF7L2-TACC2-20-AQGR | 20 (40 μL) | 200 μL |
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| TCF7L2-TACC2-20-AQAQ | 20 (40 μL) | 200 μL |
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TCF7L2 Gene Summary
This gene encodes a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt signaling pathway. The protein has been implicated in blood glucose homeostasis. Genetic variants of this gene are associated with increased risk of type 2 diabetes. Several transcript variants encoding multiple different isoforms have been found for this gene.[provided by RefSeq, Oct 2010]
Gene Name: Transcription Factor 7 Like 2
Chromosome: CHR10: 114710008 -114927436
Locus: 10q25.2-q25.3
TACC2 Gene Summary
Transforming acidic coiled-coil proteins are a conserved family of centrosome- and microtubule-interacting proteins that are implicated in cancer. This gene encodes a protein that concentrates at centrosomes throughout the cell cycle. This gene lies within a chromosomal region associated with tumorigenesis. Expression of this gene is induced by erythropoietin and is thought to affect the progression of breast tumors. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Transforming Acidic Coiled-coil Containing Protein 2
Chromosome: CHR10: 123748688 -124014057
Locus: 10q26.13
Gene Diseases
The TCF7L2 TACC2 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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