TCF7L1-WIF1 Fusion FISH Probe
The TCF7L1-WIF1 Fusion FISH Probe is used to confirm a fusion of the TCF7L1 and WIF1 genes. The fusion of the TCF7L1 and WIF1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TCF7L1-WIF1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TCF7L1-WIF1-20-RERE | 20 (40 μL) | 200 μL |
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| TCF7L1-WIF1-20-REOR | 20 (40 μL) | 200 μL |
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| TCF7L1-WIF1-20-REGO | 20 (40 μL) | 200 μL |
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| TCF7L1-WIF1-20-REGR | 20 (40 μL) | 200 μL |
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| TCF7L1-WIF1-20-REAQ | 20 (40 μL) | 200 μL |
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| TCF7L1-WIF1-20-ORRE | 20 (40 μL) | 200 μL |
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| TCF7L1-WIF1-20-OROR | 20 (40 μL) | 200 μL |
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| TCF7L1-WIF1-20-ORGO | 20 (40 μL) | 200 μL |
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| TCF7L1-WIF1-20-ORAQ | 20 (40 μL) | 200 μL |
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| TCF7L1-WIF1-20-GORE | 20 (40 μL) | 200 μL |
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| TCF7L1-WIF1-20-GOOR | 20 (40 μL) | 200 μL |
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| TCF7L1-WIF1-20-GOGO | 20 (40 μL) | 200 μL |
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| TCF7L1-WIF1-20-GOGR | 20 (40 μL) | 200 μL |
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| TCF7L1-WIF1-20-GOAQ | 20 (40 μL) | 200 μL |
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| TCF7L1-WIF1-20-GRRE | 20 (40 μL) | 200 μL |
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| TCF7L1-WIF1-20-GROR | 20 (40 μL) | 200 μL |
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| TCF7L1-WIF1-20-GRGO | 20 (40 μL) | 200 μL |
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| TCF7L1-WIF1-20-GRGR | 20 (40 μL) | 200 μL |
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| TCF7L1-WIF1-20-GRAQ | 20 (40 μL) | 200 μL |
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| TCF7L1-WIF1-20-AQRE | 20 (40 μL) | 200 μL |
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| TCF7L1-WIF1-20-AQOR | 20 (40 μL) | 200 μL |
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| TCF7L1-WIF1-20-AQGO | 20 (40 μL) | 200 μL |
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| TCF7L1-WIF1-20-AQGR | 20 (40 μL) | 200 μL |
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| TCF7L1-WIF1-20-AQAQ | 20 (40 μL) | 200 μL |
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WIF1 Gene Summary
The protein encoded by this gene functions to inhibit WNT proteins, which are extracellular signaling molecules that play a role in embryonic development. This protein contains a WNT inhibitory factor (WIF) domain and five epidermal growth factor (EGF)-like domains, and is thought to be involved in mesoderm segmentation. This gene functions as a tumor suppressor gene, and has been found to be epigenetically silenced in various cancers. [provided by RefSeq, Jun 2010]
Gene Name: WNT Inhibitory Factor 1
Chromosome: CHR12: 65444403 -65515346
Locus: 12q14.3
TCF7L1 Gene Summary
This gene encodes a member of the T cell factor/lymphoid enhancer factor family of transcription factors. These transcription factors are activated by beta catenin, mediate the Wnt signaling pathway and are antagonized by the transforming growth factor beta signaling pathway. The encoded protein contains a high mobility group-box DNA binding domain and participates in the regulation of cell cycle genes and cellular senescence. [provided by RefSeq, Nov 2010]
Gene Name: Transcription Factor 7 Like 1
Chromosome: CHR2: 85360582 -85537511
Locus: 2p11.2
Gene Diseases
The TCF7L1 WIF1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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