TCF7L1-NFASC Fusion FISH Probe
The TCF7L1-NFASC Fusion FISH Probe is used to confirm a fusion of the TCF7L1 and NFASC genes. The fusion of the TCF7L1 and NFASC genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TCF7L1-NFASC-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TCF7L1-NFASC-20-RERE | 20 (40 μL) | 200 μL |
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| TCF7L1-NFASC-20-REOR | 20 (40 μL) | 200 μL |
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| TCF7L1-NFASC-20-REGO | 20 (40 μL) | 200 μL |
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| TCF7L1-NFASC-20-REGR | 20 (40 μL) | 200 μL |
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| TCF7L1-NFASC-20-REAQ | 20 (40 μL) | 200 μL |
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| TCF7L1-NFASC-20-ORRE | 20 (40 μL) | 200 μL |
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| TCF7L1-NFASC-20-OROR | 20 (40 μL) | 200 μL |
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| TCF7L1-NFASC-20-ORGO | 20 (40 μL) | 200 μL |
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| TCF7L1-NFASC-20-ORAQ | 20 (40 μL) | 200 μL |
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| TCF7L1-NFASC-20-GORE | 20 (40 μL) | 200 μL |
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| TCF7L1-NFASC-20-GOOR | 20 (40 μL) | 200 μL |
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| TCF7L1-NFASC-20-GOGO | 20 (40 μL) | 200 μL |
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| TCF7L1-NFASC-20-GOGR | 20 (40 μL) | 200 μL |
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| TCF7L1-NFASC-20-GOAQ | 20 (40 μL) | 200 μL |
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| TCF7L1-NFASC-20-GRRE | 20 (40 μL) | 200 μL |
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| TCF7L1-NFASC-20-GROR | 20 (40 μL) | 200 μL |
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| TCF7L1-NFASC-20-GRGO | 20 (40 μL) | 200 μL |
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| TCF7L1-NFASC-20-GRGR | 20 (40 μL) | 200 μL |
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| TCF7L1-NFASC-20-GRAQ | 20 (40 μL) | 200 μL |
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| TCF7L1-NFASC-20-AQRE | 20 (40 μL) | 200 μL |
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| TCF7L1-NFASC-20-AQOR | 20 (40 μL) | 200 μL |
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| TCF7L1-NFASC-20-AQGO | 20 (40 μL) | 200 μL |
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| TCF7L1-NFASC-20-AQGR | 20 (40 μL) | 200 μL |
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| TCF7L1-NFASC-20-AQAQ | 20 (40 μL) | 200 μL |
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NFASC Gene Summary
This gene encodes an L1 family immunoglobulin cell adhesion molecule with multiple IGcam and fibronectin domains. The protein functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. This protein links the AIS extracellular matrix to the intracellular cytoskeleton. This gene undergoes extensive alternative splicing, and the full-length nature of some variants has not been determined.[provided by RefSeq, May 2009]
Gene Name: Neurofascin
Chromosome: CHR1: 204797781 -204991950
Locus: 1q32.1
TCF7L1 Gene Summary
This gene encodes a member of the T cell factor/lymphoid enhancer factor family of transcription factors. These transcription factors are activated by beta catenin, mediate the Wnt signaling pathway and are antagonized by the transforming growth factor beta signaling pathway. The encoded protein contains a high mobility group-box DNA binding domain and participates in the regulation of cell cycle genes and cellular senescence. [provided by RefSeq, Nov 2010]
Gene Name: Transcription Factor 7 Like 1
Chromosome: CHR2: 85360582 -85537511
Locus: 2p11.2
Gene Diseases
The TCF7L1 NFASC Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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