TCF7L1-DNAH6 Fusion FISH Probe
The TCF7L1-DNAH6 Fusion FISH Probe is used to confirm a fusion of the TCF7L1 and DNAH6 genes. The fusion of the TCF7L1 and DNAH6 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TCF7L1-DNAH6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TCF7L1-DNAH6-20-RERE | 20 (40 μL) | 200 μL |
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| TCF7L1-DNAH6-20-REOR | 20 (40 μL) | 200 μL |
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| TCF7L1-DNAH6-20-REGO | 20 (40 μL) | 200 μL |
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| TCF7L1-DNAH6-20-REGR | 20 (40 μL) | 200 μL |
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| TCF7L1-DNAH6-20-REAQ | 20 (40 μL) | 200 μL |
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| TCF7L1-DNAH6-20-ORRE | 20 (40 μL) | 200 μL |
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| TCF7L1-DNAH6-20-OROR | 20 (40 μL) | 200 μL |
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| TCF7L1-DNAH6-20-ORGO | 20 (40 μL) | 200 μL |
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| TCF7L1-DNAH6-20-ORAQ | 20 (40 μL) | 200 μL |
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| TCF7L1-DNAH6-20-GORE | 20 (40 μL) | 200 μL |
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| TCF7L1-DNAH6-20-GOOR | 20 (40 μL) | 200 μL |
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| TCF7L1-DNAH6-20-GOGO | 20 (40 μL) | 200 μL |
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| TCF7L1-DNAH6-20-GOGR | 20 (40 μL) | 200 μL |
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| TCF7L1-DNAH6-20-GOAQ | 20 (40 μL) | 200 μL |
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| TCF7L1-DNAH6-20-GRRE | 20 (40 μL) | 200 μL |
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| TCF7L1-DNAH6-20-GROR | 20 (40 μL) | 200 μL |
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| TCF7L1-DNAH6-20-GRGO | 20 (40 μL) | 200 μL |
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| TCF7L1-DNAH6-20-GRGR | 20 (40 μL) | 200 μL |
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| TCF7L1-DNAH6-20-GRAQ | 20 (40 μL) | 200 μL |
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| TCF7L1-DNAH6-20-AQRE | 20 (40 μL) | 200 μL |
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| TCF7L1-DNAH6-20-AQOR | 20 (40 μL) | 200 μL |
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| TCF7L1-DNAH6-20-AQGO | 20 (40 μL) | 200 μL |
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| TCF7L1-DNAH6-20-AQGR | 20 (40 μL) | 200 μL |
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| TCF7L1-DNAH6-20-AQAQ | 20 (40 μL) | 200 μL |
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DNAH6 Gene Summary
This gene belongs to the dynein family, whose members encode large proteins that are constituents of the microtubule-associated motor protein complex. This complex is composed of dynein heavy, intermediate and light chains, which can be axonemal or cytoplasmic. This protein is an axonemal dynein heavy chain. It is involved in producing force for ciliary beating by using energy from ATP hydrolysis. Mutations in this gene may cause primary ciliary dyskinesia (PCD) as well as heterotaxy. [provided by RefSeq, Jun 2016]
Gene Name: Dynein Axonemal Heavy Chain 6
Chromosome: CHR2: 84743578 -85046713
Locus: 2p11.2
TCF7L1 Gene Summary
This gene encodes a member of the T cell factor/lymphoid enhancer factor family of transcription factors. These transcription factors are activated by beta catenin, mediate the Wnt signaling pathway and are antagonized by the transforming growth factor beta signaling pathway. The encoded protein contains a high mobility group-box DNA binding domain and participates in the regulation of cell cycle genes and cellular senescence. [provided by RefSeq, Nov 2010]
Gene Name: Transcription Factor 7 Like 1
Chromosome: CHR2: 85360582 -85537511
Locus: 2p11.2
Gene Diseases
The TCF7L1 DNAH6 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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