TCF12-RGMA Fusion FISH Probe
The TCF12-RGMA Fusion FISH Probe is used to confirm a fusion of the TCF12 and RGMA genes. The fusion of the TCF12 and RGMA genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TCF12-RGMA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TCF12-RGMA-20-RERE | 20 (40 μL) | 200 μL |
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| TCF12-RGMA-20-REOR | 20 (40 μL) | 200 μL |
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| TCF12-RGMA-20-REGO | 20 (40 μL) | 200 μL |
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| TCF12-RGMA-20-REGR | 20 (40 μL) | 200 μL |
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| TCF12-RGMA-20-REAQ | 20 (40 μL) | 200 μL |
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| TCF12-RGMA-20-ORRE | 20 (40 μL) | 200 μL |
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| TCF12-RGMA-20-OROR | 20 (40 μL) | 200 μL |
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| TCF12-RGMA-20-ORGO | 20 (40 μL) | 200 μL |
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| TCF12-RGMA-20-ORAQ | 20 (40 μL) | 200 μL |
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| TCF12-RGMA-20-GORE | 20 (40 μL) | 200 μL |
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| TCF12-RGMA-20-GOOR | 20 (40 μL) | 200 μL |
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| TCF12-RGMA-20-GOGO | 20 (40 μL) | 200 μL |
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| TCF12-RGMA-20-GOGR | 20 (40 μL) | 200 μL |
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| TCF12-RGMA-20-GOAQ | 20 (40 μL) | 200 μL |
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| TCF12-RGMA-20-GRRE | 20 (40 μL) | 200 μL |
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| TCF12-RGMA-20-GROR | 20 (40 μL) | 200 μL |
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| TCF12-RGMA-20-GRGO | 20 (40 μL) | 200 μL |
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| TCF12-RGMA-20-GRGR | 20 (40 μL) | 200 μL |
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| TCF12-RGMA-20-GRAQ | 20 (40 μL) | 200 μL |
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| TCF12-RGMA-20-AQRE | 20 (40 μL) | 200 μL |
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| TCF12-RGMA-20-AQOR | 20 (40 μL) | 200 μL |
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| TCF12-RGMA-20-AQGO | 20 (40 μL) | 200 μL |
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| TCF12-RGMA-20-AQGR | 20 (40 μL) | 200 μL |
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| TCF12-RGMA-20-AQAQ | 20 (40 μL) | 200 μL |
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TCF12 Gene Summary
The protein encoded by this gene is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG. This encoded protein is expressed in many tissues, among them skeletal muscle, thymus, B- and T-cells, and may participate in regulating lineage-specific gene expression through the formation of heterodimers with other bHLH E-proteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]
Gene Name: Transcription Factor 12
Chromosome: CHR15: 57210832 -57580714
Locus: 15q21.3
RGMA Gene Summary
This gene encodes a member of the repulsive guidance molecule family. The encoded protein is a glycosylphosphatidylinositol-anchored glycoprotein that functions as an axon guidance protein in the developing and adult central nervous system. This protein may also function as a tumor suppressor in some cancers. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Gene Name: Repulsive Guidance Molecule Family Member A
Chromosome: CHR15: 93586635 -93632443
Locus: 15q26.1
Gene Diseases
The TCF12 RGMA Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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