TCF12-NPAS1 Fusion FISH Probe
The TCF12-NPAS1 Fusion FISH Probe is used to confirm a fusion of the TCF12 and NPAS1 genes. The fusion of the TCF12 and NPAS1 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TCF12-NPAS1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TCF12-NPAS1-20-RERE | 20 (40 μL) | 200 μL |
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| TCF12-NPAS1-20-REOR | 20 (40 μL) | 200 μL |
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| TCF12-NPAS1-20-REGO | 20 (40 μL) | 200 μL |
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| TCF12-NPAS1-20-REGR | 20 (40 μL) | 200 μL |
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| TCF12-NPAS1-20-REAQ | 20 (40 μL) | 200 μL |
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| TCF12-NPAS1-20-ORRE | 20 (40 μL) | 200 μL |
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| TCF12-NPAS1-20-OROR | 20 (40 μL) | 200 μL |
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| TCF12-NPAS1-20-ORGO | 20 (40 μL) | 200 μL |
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| TCF12-NPAS1-20-ORAQ | 20 (40 μL) | 200 μL |
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| TCF12-NPAS1-20-GORE | 20 (40 μL) | 200 μL |
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| TCF12-NPAS1-20-GOOR | 20 (40 μL) | 200 μL |
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| TCF12-NPAS1-20-GOGO | 20 (40 μL) | 200 μL |
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| TCF12-NPAS1-20-GOGR | 20 (40 μL) | 200 μL |
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| TCF12-NPAS1-20-GOAQ | 20 (40 μL) | 200 μL |
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| TCF12-NPAS1-20-GRRE | 20 (40 μL) | 200 μL |
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| TCF12-NPAS1-20-GROR | 20 (40 μL) | 200 μL |
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| TCF12-NPAS1-20-GRGO | 20 (40 μL) | 200 μL |
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| TCF12-NPAS1-20-GRGR | 20 (40 μL) | 200 μL |
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| TCF12-NPAS1-20-GRAQ | 20 (40 μL) | 200 μL |
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| TCF12-NPAS1-20-AQRE | 20 (40 μL) | 200 μL |
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| TCF12-NPAS1-20-AQOR | 20 (40 μL) | 200 μL |
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| TCF12-NPAS1-20-AQGO | 20 (40 μL) | 200 μL |
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| TCF12-NPAS1-20-AQGR | 20 (40 μL) | 200 μL |
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| TCF12-NPAS1-20-AQAQ | 20 (40 μL) | 200 μL |
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NPAS1 Gene Summary
The protein encoded by this gene is a member of the basic helix-loop-helix (bHLH)-PAS family of transcription factors. Studies of a related mouse gene suggest that it functions in neurons. The exact function of this gene is unclear, but it may play protective or modulatory roles during late embryogenesis and postnatal development. [provided by RefSeq, Jul 2008]
Gene Name: Neuronal PAS Domain Protein 1
Chromosome: CHR19: 47524142 -47549017
Locus: 19q13.32
TCF12 Gene Summary
The protein encoded by this gene is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG. This encoded protein is expressed in many tissues, among them skeletal muscle, thymus, B- and T-cells, and may participate in regulating lineage-specific gene expression through the formation of heterodimers with other bHLH E-proteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]
Gene Name: Transcription Factor 12
Chromosome: CHR15: 57210832 -57580714
Locus: 15q21.3
Gene Diseases
The TCF12 NPAS1 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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